INTRODUCTION The Tc-99m-ciprofloxacin complex, introduced in 1993, has been extensively evaluated all over the world with good results for the diagnosis of active bacterial osteoarticular infections. There are only a few publications on the use of this procedure in pediatric ages. In our study we evaluated the efficacy of the Tc-99m ciprofloxacin scan for the diagnosis of osteoarticular infecti...

UNLABELLED In an ongoing effort to develop a renal tracer with pharmacokinetic properties comparable to p-aminohippurate and superior to those of both (99m)Tc-mercaptoacetyltriglycine and (131)I-o-iodohippurate ((131)I-OIH), we evaluated a new renal tricarbonyl radiotracer based on the aspartic-N-monoacetic acid (ASMA) ligand, (99m)Tc(CO)(3)(ASMA). The ASMA ligand features 2 carboxyl groups and...

UNLABELLED Prostate-specific membrane antigen (PSMA) is highly expressed in prostate cancer, and small-molecule radiopharmaceuticals targeting PSMA rapidly detect the location and extent of disease. Here we evaluated preclinically 4 novel (99m)Tc-labeled small-molecule inhibitors of PSMA with the potential for clinical translation for molecular imaging of prostate cancer in humans. METHODS Fo...

UNLABELLED Early detection of heart disease is essential for the implementation of intervention strategies that reduce the risk of cardiovascular events. Radioimaging methods that have been explored for this purpose include (18)F-FDG, which measures sites of elevated metabolic activity; (99m)Tc-annexin A5, which reveals regions of enhanced apoptosis and thrombosis; and (99m)Tc-labeled anti-lect...

(99m)Tc-galactosyl human serum albumin (GSA) scintigraphy is useful to evaluate hepatic function and hepatic functional reserve. A reliable SPECT and CT integrated system is now commercially available. Using this system, we can obtain (99m)Tc-GSA SPECT/CT fused imaging with a small registration error. Therefore, the (99m)Tc-GSA scintigraphy techniques prove more useful in clinical practice than...

Introduction: Nowadays, radioisotopes have a lot of therapeutic and diagnostic applications in nuclear medicine. The technetium-99m radioisotope is widely used in the diagnostic field. The technetium-99m radioisotope is widely used in the diagnostic field. In this study, in order to increase the absorption dose in thyroid cancer cells, the radioactive drug technetium-99m which ...

The impact of MR-guided attenuation correction (compared to CT-based AC) on the diagnosis anosmia based 99m-Tc Ethyl-Cysteinate-Dimer SPECT images

introduction: the endemic occurrence of new strains of tuberculosis around the globe has initiated new research on developing diagnostic radiopharmaceutical based on antibiotics. methods:tc-99m labeled streptomycin was prepared using freshly milked 99mtco4- and various concentrations of streptomycin, stannous chloride at various temperatures in high yield radiochemical purity shown by hplc/rtlc...

urinary tract infection (uti) is a common disease in childhood specially in female. in this study 50 patients with stablished diagnosis of uti were evaluated by both renal scan with tc-99m dmsa and renal sonography. the study revealed that most urinary tract infections are in children, female sex between 5-9 years of age. therefore the most important complications (renal scarring) are also comm...

Introduction:Diethylenetriaminepentaacetic acid (DTPA) is a chelating agent used as a radiopharmaceutical compound, 99mTc-DTPA, for renography. Doxorubicin (DOX) on the other hand is an effective chemotherapy drug used to treat a variety of solid malignancies.  Both 99mTc-DTPA and DOX may be used in close succession in patients undergoing DOX based chemoth...