Variation at the pleiomorphic adenoma gene 1 (PLAG1) locus has recently been implicated in the regulation of stature and weight in Bos taurus. Using a population of 942 outbred Holstein-Friesian dairy calves, we report confirmation of this effect, demonstrating strong association of early life body weight with PLAG1 genotype. Peripubertal body weight and growth rate were also significantly asso...

Ileal permeability to different sized polyethyleneglycols (590-942 dalton PEG) was investigated peroperatively in 11 patients with Crohn's disease and seven with colonic carcinoma. A 15 cm ileal segment was converted into a tied loop, in which the PEG's were deposited. Absorption from the ileal segment was then measured as six-hour urinary recovery of the PEg dose. Polyethyleneglycol absorption...

Molecular mimicry, defined as similar structures shared by molecules from dissimilar genes or proteins, is a general strategy used by pathogens to infect host cells. Severe acute respiratory syndrome (SARS) is a new human respiratory infectious disease caused by SARS coronavirus (SARS-CoV). The spike (S) protein of SARS-CoV plays an important role in the virus entry into a cell. In this study, ...

1. Cohen MH, Williams G, Johnson JR, et al. Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. Clin Cancer Res. 2002;8:935-942. 2. Hoelzer D, Gokbuget N, Ottman OG. Targeted therapies in the treatment of Philadelphia chromosome–positive acute lymphoblastic leukemia. Semin Hematol. 2002;39(suppl 3):32-37. 3. Dager R, Cohen M, Williams G, et al. Appr...

Parents and teachers often express concern about the extensive use of social media by youngsters. Some of them see emoticons, undecipherable initialisms and loose grammar typical for social media as evidence of language degradation. In this paper, we use a simple measure of text complexity to investigate how the complexity of public posts on a popular social networking site changes over time. W...

Diabetic mellitus (DM) is a disease that affects glucose homeostasis and causes complications, such as diabetic nephropathy (DN). For early diagnosis of DN, microalbuminuria is currently one of the most frequently used biomarkers. However, more early diagnostic biomarkers are desired in addition to microalbuminuria. In this study, we performed comprehensive proteomics analysis of urine proteome...

as a lead pencil. It is hypospadic and the urethra opens on its under surface near its root. Urine passes into the vagina-like opening. Gives a history of first menstruating at 15 years of age, and has menstruated three times, the last time about 20 days ago. Has been married for the past 6 years. Husband living. Uterus and ovaries cannot be felt, they are probably rudimentary. No opening could...

Abstract The quality of the components fabricated using fusion deposition modelling (FDM) can be tailored by proper selection process parameters values. Print orientation is a key parameter in FDM which has strong influence on defect formation and thereby mechanical properties components. To address print orientation, Polyethylene terephthalate glycol (PETG) samples were tested. different orien...

• Overdiagnosis of lyme borreliosis (LB) leads to unnecessary, and sometimes prolonged, antimicrobial treatments. None our 15 patients with a presumed diagnosis LB receiving treatment for at least 6 months were diagnosed LB. Nine mental disorder. overtreatment put risk undiagnosed illnesses multiple adverse effects unjustified The clinical management such requires comprehensive approach includi...

Nghiên cứu có mục đích là tìm hiểu, đánh giá chính xác các đặc điểm dậy thì hoàn toàn của học sinh trung cơ sở tại Hà Nội. được thực hiện trên nhóm đối tượng bao gồm 1.926 (942 nam và 984 nữ) độ tuổi từ 12 đến 15 3 trường (Dịch Vọng, Tây Sơn Vân Hòa) thuộc quận, huyện thành phố Kết quả nghiên cho thấy, bình nữ sớm hơn so với 1 năm 2 tháng. Tuổi Nội cũng một số khác trong nước. Từ những kết giúp...