Efficient and one-pot synthesis of 1,8-dioxo-octahydroxanthenes was described by Knoevenagel condensation, Michael addition and cyclodehydration of dimedone. This reaction was carried out through condensation of dimedone and various aromatic aldehydes in the presence of task-specific Brønsted acidic ionic liquid under solvent free conditions. The catalyst could be recycled five times without si...

In the title salt, NH(4) (+)·C(4)H(3)N(2)O(2)S(-), the asymmetric unit comprises two half-occupied ammonium positions and a 4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-ide anion. The anion shows C(2) as well as C(s) symmetry and is present in its diketonic tautomeric form. Intra-cyclic angles span a range from 116.64 (9)-124.67 (9)°. Inter-molecular N-H⋯O hydrogen bonds connect the cations and ani...

methylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride hemiethanol hemihydrate (Fig. 1), is one of the tetracycline derivatives, which has a wide range of antibacterial activities. DOX is frequently used to treat chronic prostatitis, sinusitis, syphilis, chlamydia, pelvic inflammatory disease, acne, rosacea, and rickettsia...

In the presence of strong bases (NaH, DBU, KOH), ethyl 4-chloromethyl-6-methyl-2-oxo1,2,3,4-tetrahydropyrimidine-5-carboxylate and 4-mesyloxymethyl-6-methyl-5-tosyl-1,2,3,4tetrahydropyrimidin-2-one are transformed into novel tricyclic compounds, diethyl 9-methyl-5methylene-3,11-dioxo-2,3,4,5,6a,7,10,11-octahydro-1,6-methano[1,3]diazepino[1,7-e][1,3,5]triazocine-6,8(1H)-dicarboxylate and 9-methy...

New benzo[a]naphthacenequinone metabolites, designated bequinostatins A and B, have been isolated from the culture broth of the benastatin-producing strain Streptomyces sp. MI384-DF12. The structures of bequinostatins A and B were determined by spectral analyses to be 5,6,8,13-tetrahydro-1,6,7,9,11-pentahydroxy-8,13-dioxo-3- pentylbenzo[a]naphthacene-2-carboxylic acid and 2-decarboxybequinostat...

In the title compound, [Cu(CH(3)CO(2))(C(12)H(11)N(2)O(4))(H(2)O)](n), the Cu(II) cation is tetra-coordinated by three carboxyl-ate O atoms from one 4-[N'-(2,4-dioxo-3-pentyl-idene)-hydrazino]-benzoate ligand and two acetate bridges, and by one water mol-ecule. The acetate bridges link adjacent Cu(II) cations, forming a chain. The crystal structure involves O-H⋯O hydrogen bonds.