Four positively-charged residues, namely betaLys-155, betaArg-182, betaArg-246, and alphaArg-376 have been identified as Pi binding residues in Escherichia coli ATP synthase. They form a triangular Pi binding site in catalytic site betaE where substrate Pi initially binds for ATP synthesis in oxidative phosphorylation. Positive electrostatic charge in the vicinity of betaArg-246 is shown to be ...

Pan African Medical Journal. 2016; 24:246 doi:10.11604/pamj.2016.24.246.6841 This article is available online at: http://www.panafrican-med-journal.com/content/article/24/246/full/ © Kieran Walsh et al. The Pan African Medical Journal ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0...

Strain 768-28 was isolated from a hot spring in Kamchatka, Russia, and represents a novel member of the Vulcanisaeta genus. The complete genome sequence of this thermoacidophilic anaerobic crenarchaeon reveals genes for protein and carbohydrate-active enzymes, the Embden-Meyerhof and Entner-Doudoroff pathways for glucose metabolism, the tricarboxylic acid cycle, beta-oxidation of fatty acids, a...

seven hundred and sixty-eight blood samples of pregnant cattle from four holstein dairy herds that are farmed in the vicinity of tehran were used to evaluate the seroprevalence of neospora caninum infection by enzyme-linked immunosorbent assay (elisa). two hundred and ninety-eight of the 768 blood samples (38.8%) were positive for this infection. the prevalence of infection in the herds varied ...

Background Between 30 and 40% of human breast cancers express a defective tumor suppressor p53 gene. Wild-type p53 tumor suppressor protein promotes cell-cycle arrest and apoptosis and inhibits vascular endothelial growth factor-dependent angiogenesis, whereas mutant p53 protein (mtp53) lacks these functions, resulting in tumor cell survival and metastasis. Restoration of p53 function is theref...

CORRESPONDENCE: B. Van de Maele, Respiratory Division, Henri Serruys Hospital, Kaı̈rostraat 84, B-8400 Oostende, Belgium. Fax: 32 59555792. E-mail: dr.vandemaele@henriserruysav.be *Respiratory Division, Dept of Surgery, and Dept of Pathology, Henri Serruys Hospital, and Torhoutsesteenweg 51, B-8400, Oostende, Belgium. Eur Respir J 2005; 25: 768–770 DOI: 10.1183/09031936.05.00110904 Copyright ERS...

This paper is concerned with applications of Tutte’s barycentric embedding theorem (1963, Proc. London Math. Soc. 13, 743–768). It presents a method for building isotopies of triangulations in the plane, based on Tutte’s theorem and the computation of equilibrium stresses of graphs by Maxwell–Cremona’s theorem; it also provides a counterexample showing that the analogue of Tutte’s theorem in di...

First (DI) and second (D2) order derivative spectrophotometric method with an application of base line to peak technique was used for determination of active pharmaceutical ingredients (API) at two wavelengths: fluphenazine (D1 at lambda = 251 nm and lambda = 265 nm, D2 at lambda = 246 nm and lambda = 269 nm), pernazine (D1 at lambda = 246 nm and lambda = 258 nm, D2 at lambda = 254 nm and lambd...

Kenk, Roman. Freshwater Triclads (Turbellaria) of North America, IX: The Genus Sphalloplana. Smithsonian Contributions to Zoology, number 246, 38 pages, 62 figures, 1 table.—A revision of the North American species of the genus Sphalloplana is presented. Apart from the nine species already known (S. percoeca, S. georgiana, S. kansensis, S. virginiana, S. weingartneri, S. buchanani, S. pricei, S...