PURPOSE Airway remodeling may be responsible for irreversible airway obstruction in asthma, and a low post-bronchodilator FEV1/FVC ratio can be used as a noninvasive marker of airway remodeling. We investigated correlations between airway wall indices on computed tomography (CT) and various clinical indices, including post-bronchodilator FEV1/FVC ratio, in patients with asthma. METHODS Volume...

Methacholine inhalation challenge (MIC) is probably the most widely used and best standardized test for nonspecific bronchoprovocation challenge (BPC). There has been increasing interest in developing "physical" stimuli such as eucapnic voluntary hyperventilation (EVH) with dry gas to assess airway hyperreactivity (AHR), because of inherent problems with using a pharmacologic agent in epidemiol...

The paper proposed that predation, especially that which prevented spatial monopolization by a competitively dominant species, maintained or enhanced local species diversity. The viewpoint was supported by a controlled field experiment involving starfish removal, and observed subsequent decline in community species richness. [The SCI indicates that this paper has been cited over 275 times since...

The waste water generation from the automobile motor workshop activities are responsible for environmental degradation in form of pollution and showed variable impact on plant growth. This paper gives information, assessment screening about effect work shop seedling growth two different types legume bean crops namely, kidney (Phaseolus vulgaris L.) mung (Vigna radiata (L.) R. Wilkczek) pot cult...

R. C. Larson Service industries comprise roughly 75 percent of the gross domestic product of developed nations. To design and operate service systems for today and tomorrow, a new type of engineer must be educated, one who focuses on services rather than manufacturing. Such an engineer must be able to integrate three sciences— management, social, and engineering science—in the analysis of servi...

The "R-75" strain live, attenuated, serum inhibitor-resistant influenza B vaccine was administered intranasally by drops in two doses 14 days apart to 21 volunteers. Each vaccinee was paired with a close associate (roommate or workmate) who similarly received two doses of a placebo solution. Although about 50% of both vaccine and placebo recipients complained of symptoms after dosage, the sever...

1. L. A. Sherman and R. M. Brown, in Comprehensive Virology, H. Frankel-Conrat and R. R. Wagner, Eds. (Plenum, New York, 1978), vol. 12, p. 145. 2. P. A. Lemke, Annu. Rev. Microbiol. 30, 105 (1976); J. A. Dodds, Experientia 35,.440 (1979). 3. A. Skotnicki, A. J. Gibbs, N. G. Wrigley, Virology 75, 457 (1976); J. A. Dodds and A. Cole, ibid. 100, 156 (1980); A. Cole, J. A. Dodds, R. I. Hamilton, i...