نتایج جستجو برای: 68ga psma petct scanning

تعداد نتایج: 162982  

Journal: :Egyptian Journal of Radiology and Nuclear Medicine 2022

Abstract Background Consensus statements was published by EAU and EANM to clarify some uncertainties on PSMA PET/CT response assessment in 2020. We aimed investigate the criteria for according comparing with serum PSA changes determine factors affecting therapy evaluation. Results A high concordance found between [ 68 Ga]Ga-PSMA-11 responses 0.84 of Gamma coefficient obtained. Between concordan...

Journal: :Molecules 2015
Irina Velikyan

The contribution of 68Ga to the promotion and expansion of clinical research and routine positron emission tomography (PET) for earlier better diagnostics and individualized medicine is considerable. The potential applications of 68Ga-comprising imaging agents include targeted, pre-targeted and non-targeted imaging. This review discusses the key aspects of the production of 68Ga and 68Ga-based ...

2017
M. Meckel R. Bergmann M. Miederer F. Roesch

Background Bisphosphonates have a high adsorption on calcified tissues and are commonly used in the treatment of bone disorder diseases. Conjugates of bisphosphonates with macrocyclic chelators open new possibilities in bone targeted radionuclide imaging and therapy. Subsequent to positron emission tomography (PET) examinations utilizing 68Ga-labelled analogues, endoradiotheraphy with 177Lu-lab...

2017
George Hruby Thomas Eade Andrew Kneebone Louise Emmett Lesley Guo Bao Ho Ed Hsiao Geoff Schembri Julia Hunter Carol Kwong

Background and purpose: We investigated the role of Ga-PSMA-PET (PSMA) to determine the location of disease recurrence in those with a rising PSA following definitive external beam radiation treatment (EBRT). Materials and methods: 538 men were treated with image guided EBRT to a dose of 78 or 82 Gy between 2007 and 2014. Patients at least 24 months post EBRT with biochemical failure (nadir + 2...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2007
Robert J Durso Sofija Andjelic Jason P Gardner Dennis J Margitich Gerald P Donovan Robert R Arrigale Xinning Wang Maureen F Maughan Todd L Talarico Robert A Olmsted Warren D W Heston Paul J Maddon William C Olson

PURPOSE Prostate-specific membrane antigen (PSMA) is an attractive target for active immunotherapy. Alphavirus vaccines have shown promise in eliciting immunity to tumor antigens. This study investigated the immunogenicity of alphavirus vaccine replicon particles (VRP) that encode PSMA (PSMA-VRP). EXPERIMENTAL DESIGN Cells were infected with PSMA-VRP and evaluated for PSMA expression and fola...

2005
Krasimira Todorova Irena Ignatova Stoyan Tchakarov Iskra Altankova Serguei Zoubak Stanimir Kyurkchiev Milcho Mincheff

Prostate-specific membrane antigen (PSMA), whose expression is upregulated in poorly differentiated, metastatic, and hormone refractory prostate cancer, could be targeted by gene-based vaccines. The aim of this study was to characterize the humoral immune response against PSMA in prostate carcinoma patients who have been vaccinated against PSMA with gene-based vaccines. Sera from prostate cance...

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