PURPOSE To evaluate the effect of common three photon energies (6-MV, 10-MV, and 15-MV) on intensity-modulated radiation therapy (IMRT) plans to treat prostate cancer patients. MATERIALS AND METHODS Twenty patients with prostate cancer treated locally to 81.0 Gy were retrospectively studied. 6-MV, 10-MV, and 15-MV IMRT plans for each patient were generated using suitable planning objectives, ...

PURPOSE Flattening filter free (FFF) beams in radiotherapy have advantages such as shorter treatment delivery time and lower out-of-field dose compared with conventional flattened beams. This study investigates in detail the skin dose induced by FFF beams from a TrueBeam accelerator (Varian Medical Systems, Palo Alto, CA) using Monte Carlo method. METHODS Phase space files generated using rea...

This study evaluates changes in the dosimetric characteristics of a Varian Millennium 80-leaf multileaf collimator (MLC) in a radiation field. In this study, dose rate, scatter factor, percentage depth dose, surface dose and dose in the buildup region, beam profile, flatness and symmetry, and penumbra width measurements were made for 6-MV and 15-MV photon beams. Analysis of widths between 50% d...

The main purpose of this work is to demonstrate a practical means of determining the leaf transmission and scatter characteristics of a multileaf collimator (MLC) pertinent to the commissioning of dynamic intensity modulated radiotherapy, especially for the sweeping window technique. The data are necessary for the conversion of intensity distributions produced by intensity-modulated radiotherap...

PURPOSE To analyze the distribution of functional liver volume (FLV) in the margin volume (MV) surrounding hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) before radiation therapy (RT) and to verify the safety of single photon emission computed tomography-based three-dimensional conformal radiotherapy (SPECT-B3DCRT) by exploring the relation of FLV in MV to radiation-induc...

Craniospinal is known as the method to kill cancer within a wide radiation area, starting from cranial spinal nervous system. In case, has spread through fluid of cerebro spinalis, such medulloblastoma. We carried out research determine isodose curve in medulloblastoma craniospinal patients and DVH (Dose Volume Histogram) statistic OAR (Organ at Risk) by using 3D-CRT radiotherapy technique. To ...

PURPOSE The aim of this study is to quantify and to compare the dose enhancement factor from gold nanoparticles (AuNP) to tumor endothelial cells for different concentrations of AuNP, and clinical MV beam configurations. METHODS Tumor endothelial cells are modeled as slabs measuring 10 × 10 × 2 μm. A spherical AuNP is simulated on the surface of the endothelial cell, within the blood vessel. ...