نتایج جستجو برای: 5 oxadiazole
تعداد نتایج: 1216478 فیلتر نتایج به سال:
A novel series of 1,3,4-oxadiazole derivatives containing a 5-phenyl-2-furan moiety were synthesized from the intermediates diacylhydrazine 3 and acylhydrazone 5 via an efficient approach under microwave irradiation in good yields. Their structures were characterized by IR, (1)H NMR, and elemental analysis. The antifungal tests indicated that the title compounds showed in vivo fungicidal activi...
Synthesis and Antibacterial Activity of 2-(2-(Cyclopropylmethoxy) Phenyl)-5-Methyl-1,3,4- Oxadiazole
Treatment of [PdCl2(dppf)].CH2Cl2 or [PtCl2(dppf)] with two moles 2-(benzylthio)-5-phenyl-1,3,4-oxadiazole (bpozs) in (ethanol: chloroform) solvents for (2 h) afford [M(bpozs)2(dppf)]Cl2 good yield. The synthesized ligand and complexes were identified using FT-IR, 1H-NMR, 13C-NMR, 13P-NMR, CHNS analysis, Uv-Visible spectra conductivity measurements. physiochemical data ...
Novel conformationally restricted analogues of agomelatine were synthesized and pharmacologically evaluated at MT₁ and MT₂ melatoninergic receptors. Replacement of the N-acetyl side chain of agomelatine by oxathiadiazole-2-oxide (compound 3), oxadiazole-5(4H)-one (compound 4), tetrazole (compound 5), oxazolidinone (compound 7a), pyrrolidinone (compound 7b), imidazolidinedione (compound 12), thi...
The S-(5-aryl-1,3,4-oxadiazol-2-yl) O-alkyl carbonothioate (4-9) and the alkyl 2-((5-aryl-1,3,4-oxadiazol-2-yl)thio) acetate (10-15) were synthesized by interaction of 5-aryl-1,3,4-oxadiazole-2-thiones with esters chloroformic acid chloroacetic acid. yields target compounds (7-9) obtained isobutyl chloroformate 69-73%, (4-6) propyl - 74-79% 86-92%, respectively. structures confirmed IR, UV, 1H ...
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