5-hydroxymethylfurfural (HMF) is an aromatic compound that admitted indicator of reduced quality in different foodstuffs. Here, a novel, sensitive, and simple online solid-phase extraction (SPE) based on molecularly imprinted sol-gel polymer (MIS) coupled to HPLC-UV was designed developed for the determination HMF. Under optimum conditions, good linearity achieved from 0.03 0.45 μg ml-1 with re...

Hydroxymethylfurfural (HMF), a well-known heterocyclic Maillard reaction product, has often been studied for its potential toxic, mutagenic, and carcinogenic effects. Recent clinical studies, however, have strongly suggested that HMF might have exciting antitumor potential. We report on the development and validation of a bioanalytical assay for HMF that could be suitable as a basis for pharmac...

Hydroxymethylfurfural is a product of food deterioration and is still under investigation for possible toxic effects. It can also be used to monitor food quality. A sensitive and selective LC/MS method for monitoring this compound is presented. The method can quantitatively determine hydroxymethylfurfural in food with a detection limit of 0.005 μg/g. Sample preparation and analytical conditions...

Background and Objectives: Furfural (F) and hydroxymethyl furfural (HMF) are cyclic aldehydes, which are formed during the heat processing of foods. These chemical contaminants have received much attention due to their suspected health hazards and heat damage indicators. The aim of the present study was extraction and determination of F and HMF in baby-foods using dispersive liquid-liquid micro...

BACKGROUND In 5%-10% of patients with of chronic myelogenous leukemia (CML), the Philadelphia chromosome (Ph) is not identified, despite the presence of the associated BCR-ABL molecular abnormality (Ph-negative, BCR-ABL-positive CML) because of sub-microscopic rearrangements. PATIENTS AND METHODS Six patients with Ph-negative, BCR-ABL-positive CML were investigated. The Ph chromosome detectio...

BACKGROUND: Invasive Cronobacter infection is rare, devastating, and epidemiologically/microbiologically linked to powdered infant formulas (PIFs). In 2002–2004, the US Food and Drug Administration advised health care professionals to minimize PIF and powdered human milk fortifier (HMF)’s preparation, feeding, and storage times and avoid feeding them to hospitalized premature or immunocompromis...

BACKGROUND: Invasive Cronobacter infection is rare, devastating, and epidemiologically/microbiologically linked to powdered infant formulas (PIFs). In 2002–2004, the US Food and Drug Administration advised health care professionals to minimize PIF and powdered human milk fortifier (HMF)’s preparation, feeding, and storage times and avoid feeding them to hospitalized premature or immunocompromis...

The effects of food components on blood fluidity were studied by in vitro assay using a dedicated microchannel instrument for model capillaries. We found that the fruit-juice concentrate of the Japanese apricot (Prunus mume Sieb. et Zucc), a traditional Japanese food, markedly improved the fluidity of human blood. Using HPLC, we isolated the active compounds and characterized them using UV, MS,...