نتایج جستجو برای: 475 cm
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Abstract Introduction Sleep disordered breathing is a significant risk factor for cardiometabolic and neurodegenerative diseases. Tolerance efficacy of continuous positive airway pressure (CPAP), the primary form therapy sleep apnea, often poor. High loop gain (HLG) driving mechanism central apnea or periodic breathing. The current study aimed to develop computational approach detect HLG based ...
The usefulness of targeted molecular dynamics (TMD) for the simulation of large conformational transitions is assessed in this work on the unfolding process of chymotrypsin inhibitor 2 (CI2). In TMD the force field is supplemented with a harmonic restraint which promotes either the increase of the conformational distance from the native state or the decrease of the distance from a target unfold...
Inactivation of the visual G-protein transducin by GTP hydrolysis is regulated by the GTPase-accelerating protein (GAP) RGS9-1. Regulation of RGS9-1 itself is poorly understood, but we found previously that it is subject to a light- and Ca(2+)-sensitive phosphorylation on Ser(475). Because there are much higher RGS9-1 levels in cones than in rods, we investigated whether Ser(475) is phosphoryla...
Abstract Linked Article: Eshagh et al. Br J Dermatol 2022; 187:318–323.
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