In this study, in order to find novel biologically active penta-1,4-dien-3-one derivatives, a series of penta-1,4-dien-3-one compounds containing a substituted pyrazole subunit were designed and synthesized. Their structures were characterized by ¹H-NMR, 13C-NMR and elemental analysis. The preliminary bioassays displayed that most of the title compounds showed significant antiproliferative acti...

A study was made of the methyl sterols involved in sterol biosynthesis in developing rat brain. In addition to the determination of the endogenous sterols present in 15-day-old rat brain, experiments were conducted to establish which of these sterols could be labeled by a minced tissue preparation in the presence of [Z-W]mevalonic acid. The turnover of [14C]lanostero1, [4-3H]squalene oxide, and...

Three solvothermal systems Ln/As/Se/en, Ln/As/Se/dien and Ln/As/Se/(en+trien) (Ln = lanthanide excluding Pm, en = ethylenediamine, dien = diethylenetriamine, trien = triethylenetetramine) were investigated in detail across the lanthanide series, and ternary lanthanide selenidoarsenates [Ln(en)(3)(H(2)O)(mu-eta(1),eta(1)-AsSe(4))] (Ln = La(1a), Ce(1b), Nd(1c)), [Ln(en)(4)]AsSe(4) x 0.5 en (Ln = ...

The title compound, C(13)H(10)OS(2), exhibits twists between the central C(3)O and ethene residues [O-C-C-C torsion angles = -8.4 (3) and 11.8 (3)°], and between the ethene and adjacent thio-phenyl residues [C-C-C-C torsion angles = -4.2 (3) and 10.5 (3)°]. As a result, the mol-ecule is non-planar, the dihedral angle formed between the terminal thio-phenyl groups being 15.45 (10)°. The presence...

The title compound, [Ti(C(15)H(23)N(2)Si)Cl(3)]·0.5C(4)H(8)O, has been prepared from {2-[2-(η(5)-cyclo-penta-dien-yl)-2-methyl-prop-yl]-1H-imidazolyl-κN(1)}bis-(N,N-diethyl-amido-κN)titanium(IV), (C(12)H(14)N(2))Ti(NEt(2))(2), by reaction with excess of Me(3)SiCl in tetra-hydro-furan (THF) at 353 K. The crystal structure contains THF as adduct solvent, disordered around a center of inversion. T...