A new synthetic pathway to various mono-alkyl-substituted phosphinoboranes HRP–BH2–NMe3 has been developed. The route starting from alkyl halides and NaPH2 followed by metalation salt metathesis is performed in a one-pot procedure leads higher yields purity of the resulting phosphinoboranes, as compared previously reported routes. Additionally, scope accessible compounds could be expanded short...

structurally different trimethyl silyl ethers are oxidized with bu4/nio4 in the presence of alcl3 and bf3 as catalysts in ch3cn and chcl3 under reflux conditions. the corresponding carbonyl compounds are isolated in good yields.

Isoxazoline γ-lactams are prepared starting from the regioisomeric cycloadducts of benzonitrile oxide to the N-alkyl 2-azanorbornenes taking advantage of the efficient catalytic oxidation by RuO(4). The reduction of the amide groups is easily conducted in the presence of LiAlH(4) under mild conditions, which allowed for the chemoselective reduction of the amide moiety followed by ring opening t...

1. The progressive development of resistance to reactivation by an oxime (;aging') shown by a series of alkyl methylphosphonyl-acetylcholinesterases is slow when the alkyl group is a primary alcohol, whether or not the carbon chain is branched, but is much more rapid if the alkyl group is a secondary or cyclic alcohol. 2. Aging is accelerated by increase of temperature or decrease of pH. 3. Agi...

Six novel 3-alkyl(aryl)-4-(p-nitrobenzoylamino)-4,5-dihydro-1H-1,2,4-triazol-5- ones (2a-f) were synthesized by the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H- 1,2,4-triazol-5-ones (1a-f) with p-nitrobenzoyl chloride and characterized by elemental analyses and IR, (1)H-NMR, (13)C-NMR and UV spectral data. The newly synthesized compounds 2 were titrated potentiometrically with tetrabutyla...

zinc ferrite (znfe2o4) nanoparticles were synthesized via the auto-combustion assisted sol-gel method of zn2+ and fe3+ ions (molar ratio 1:2) in ammonia solution. the prepared nanomagnetic catalyst was characterized by ir, xrd, sem and icp. the diameter of the znfe2o4 mnps (63.7 nm) was determined by debye-scherre equation via their xrd pattern. nanomagnetic znfe2o4 efficiently catalyzes oxidat...

A series of alkyl nitrohydroxytyrosyl ether derivatives has been synthesized from free hydroxytyrosol (HT), the natural olive oil phenol, in order to increase the assortment of compounds with potential neuroprotective activity in Parkinson's disease. In this work, the antioxidant activity of these novel compounds has been evaluated using Ferric Reducing Antioxidant Power (FRAP), 2,2'-azinobis(3...

Reaction of 7-hydroxy-4-methyl coumarin with amido/ imido alcohols in ethanol containing concentrated hydrochloric acid afforded 8-aralkyl amido/imido-alkyl-7-hydroxy-4-methyl-coumarins (1a-f). Interaction of 1a-f with hydrazine hydrate in pyridine resulted in 1-amino-8-aralkyl amido/imido-alkyl-7-hydroxy-4-methyl-2-oxo-quinolines (2a-f). Treatment of 2 with formaldehyde in ethanol resulted in ...