Background: To evaluate computed tomography (CT) and magnetic resonance imaging (MRI) fusion images for delineating gross tumor volume (GTV) in three-dimensional conformal radiotherapy (3D-CRT) of nasophanrygeal carcinoma (NPC), and compare treatment outcomes between CT- and CT+MRI-based targets. Materials and Methods: A total of 120 NPC patients treated with 3D-CRT were included, in which, 60 ...

Cardiac resynchronization therapy (CRT) can alleviate left ventricular (LV) electrical dyssynchrony mediated systolic heart failure (HF). 15% reduction in LV end volume (LVESV) with CRT is a validated surrogate of improved clinical outcomes. Prolonged baseline QRS duration (QRSd) the only conventional quantitative ECG criteria to assess dyssynchrony. In addition duration, we evaluated voltage-t...

BACKGROUND Whether mechanical dyssynchrony indices predict reverse remodeling (RR) or clinical response to cardiac resynchronization therapy (CRT) remains controversial. This prospective study evaluated whether echocardiographic dyssynchrony indices predict RR or clinical response after CRT. METHODS AND RESULTS Of 184 patients with heart failure with anticipated CRT who were prospectively enr...

OBJECTIVES The goals of this study were to compare patterns of mechanical activation in patients with chronic right ventricular (RV) pacing with those with left bundle branch block (LBBB) using 2-dimensional and novel 3-dimensional speckle tracking, and to compare ejection fraction (EF) response and long-term survival after cardiac resynchronization therapy (CRT). BACKGROUND Several randomize...

Background: Radiation-induced cardiac events and pneumonitis are the major late radiotherapy side effects. Methods: We explored differences in dose distribution between 3D CRT, IMRT VMAT 125 women with unilateral breast cancer. The various to tumor OARs were studied for left right sided irradiation. Results: Upon using CRT breasts lymph nodes, we observed a significant increase ipsilateral lung...

The benefits of hypofractionated radiotherapy with FAST and FAST-forward protocols could be compromised by soft tissue reactions cardiac toxicity caused dose inhomogeneity inaccurate heart sparing. This study aims to evaluate the dosimetric results whole-breast field-in-field 3D conformal (3D-CRT) technique. A mono-institutional consecutive cohort 122 early-stage invasive breast cancer patients...

Background: We compared 3D-conformal radiation therapy (3D-CRT) and intensity-modulated (IMRT) planning for left-sided post-mastectomy patients. Aim: To compare the dose coverage of target volume (PTV) delivered to organs at risk (OAR) 3D-CRT IMRT plans. Setting: Department Oncology, central South Africa. Methods: Twenty-six archived CT scans patients with breast cancer were included. The plans...

The Anaglyph 3D method of stereoscopic visualization is both cost effective and compatible with all full-color displays, however this method often suffers from poor 3D image quality due to poor color quality and ghosting (whereby each eye sees a small portion of the perspective image intended for the other eye). Ghosting, also known as crosstalk, limits the ability of the brain to successfully ...

Conformal radiotherapy (CRT) results in high-precision tumor volume irradiation. In fractioned radiotherapy (FRT), lesions are irradiated in several sessions so that healthy neighbouring tissues are better preserved than when treatment is carried out in one fraction. In the case of intracranial tumors, classical methods of patient positioning in the irradiation machine coordinate system are inv...