Regorafenib is an oral multikinase inhibitor approved for advanced mCRC, gastrointestinal stromal tumors, and hepatocellular carcinoma. The phase 2 regorafenib dose-optimization study (ReDOS; Bekaii-Saab TS, et al., 2019) demonstrated that patients could initiate at a dose of 80 mg/day then subsequently escalate their depending on tolerability without compromising efficacy. In March 2018, the R...

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In recent years, buffalograss, Buchloë dactyloides (Nuttall) Engelmann has gained popularity as a turfgrass because of its low maintenance requirement, drought tolerance, and limited pests and diseases. Within the last decade, however, the western chinch bug Blissus occiduus Barber has emerged as important pest of buffalograss. Considerable progress has been made toward identifying buffalograss...

In 313 consecutive recipients of 393 orthotopic liver grafts, there were 51 (16.3%) and nine (2.9%) patients who had pre-existing portal vein and inferior vena cava abnormalities, respectively. These abnormalities required adjustments in the transplant operation and were a source of morbidity and mortality. The incidence of thrombosis of the reconstructed portal vein was 1.8%. Only three (0.8%)...

© Lippincott Williams & Wilkins S1 From the aDepartment of Zoology, Brigham Young University, Provo, Utah, USA and bSAIC Frederick, Frederick Cancer Research & Development Center, National Cancer Institute, Frederick, Maryland, USA. Sponsorship: This work was supported by a James A. Shannon Award, an Alfred P. Sloan Award, and NIH grant #R01 HD34350-01A1. Correspondence to Dr Keith A. Crandall,...

0022-1694/$ see front matter 2013 The Authors. Published by Elsevier B.V. All rights reserved. http://dx.doi.org/10.1016/j.jhydrol.2013.03.050 q This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. ⇑ Corresponding ...