PURPOSE Biodegradable nanoparticles (NPs) composed of poly(D, L-lactide-co-glycolide) (PLGA) have attracted considerable attention as delivery systems of drugs and antioxidative compounds, such as β-carotene (BC). Intravenous (IV) administration of BC-containing PLGA-NPs (BC-PLGA-NPs) coated with polysorbate 80 (PS80) has been shown to effectively deliver BC to the brain. However, the whole-bod...

Introduction: The growing trend of cancer incidence in the past few decades and its effects on physical, psychological, spiritual, and social dimensions both in patients and their families make cancer one of the major health hazards of the century. Of all cancers, breast cancer (BC) is the most prevalent among females. Thus, the current study aimed at comparing three components of BC between fe...

Introduction: Dietary acid load contributes to metabolic acidosis, closely linked to cancer development through inflammation and cell transformation. There is very limited epidemiologic evidence; linking diet-dependent acid load and cancer risk. Since there are few published studies specifically on urinary pH and bladder cancer (BC) risk, we sought to explore this association in the present stud...

Introduction: Vestibular evoked myogenic potential (VEMP) has recently been broadly studied in vestibular disorders. As it is evoked by loud sound stimulation, even mild conductive hearing loss may affect VEMP results. Bone-conducted (BC) stimulus is an alternative stimulation for evoking this response. This study aims to assess the characteristics of BC-VEMP in different groups of patients.   ...

OBJECTIVES Extensive peritumoral neoplastic lymphovascular invasion (ePVI) is a marker of aggressiveness in invasive breast carcinoma (BC). METHODS We explored the impact of ePVI on different BC subtypes. In a total of 2,116 BCs, 91 ePVI-BCs, 70 inflammatory breast carcinomas (IBCs), and 114 casual BCs as a control group (CG-BC) were recruited. RESULTS Patients affected by ePVI-BC were youn...