Many therapeutic options have been suggested for the treatment of vitiligo including non-surgical and surgical modalities. Non-surgical modalities, considered the first line therapy, include topical, intra-lesional and systemic corticosteroids, topical and oral psoralen plus ultraviolet A (PUVA), topical khellin 3%-4%-5%, broadband and narrow-band UVB (311 nm UVB phototherapy), and recently, to...

Coherent radiation at several wavelengths in the vacuum ultraviolet (VUV) has been generated by four-wave parametric oscillation in mercury vapor. When a powerful ultraviolet pump laser of frequency omega(p) is tuned to a two-photon resonance, VUV signal photons at frequency omega(s), as well as idler photons at frequency omega(i), are generated such that omega(s) + omega(i) = 2omega(p). A freq...

A new custom-built excimer (193 nm) laser-ablation system with two-volume laser-ablation cell coupled to a quadrupole ICPMS is described, which combines rapid (<1.5 s for 99%) signal washout with full flexibility in sample size (50 50 25 mm) and high sensitivity (>10000 cps/ppm for mid-high m/z, 55 mm, 5 Hz). An application of reconstructing medieval Pb exposure highlights the need for rapid si...

This article presents a method used to guide the beam from an argon fluoride excimer laser to make it suitable for microsurgical purposes and confine it to areas that can be varied in dimension from 1 micron to tens or hundreds of microns. This approach guides the excimer laser beam with an articulated mechanical arm and confines it with variable-diameter tapered tubes, possibly allowing the us...

Ultrashort pulses were produced at 248 nm by using a transverse-discharge KrF* excimer laser as a high-energy amplifier system. Input pulses for the amplifier system were obtained by upconverting the output of a modelocked visible dye laser to the ultraviolet by using nonlinear crystals. Pulses of up to 20 mJ; in energy with 10-30-psec duration were obtained at 10 pulses/sec. The output pulse w...

Subpicosecond vacuum-ultraviolet radiation at 155 nm with pulse energies above 0.2 mJ has been obtained by near-resonant four-wave difference-frequency mixing in a Xe gas jet. Laser fields for the mixing process have been generated by a short-pulse KrF dye excimer laser system and a Raman converter. The process permits tuning in a broad vacuum-ultraviolet range and can be scaled up to higher ou...

We propose and demonstrate a new method for fabricating periodic arrays of metal nanodots over a large area. In this method, metal nanogratings were first patterned on a substrate by nanoimprint lithography and lift-off, and were then melted using a single excimer laser pulse. We found that the laser melting broke the metal nanogratings into periodic nanodots. Furthermore, we demonstrated the c...

PURPOSE To evaluate whether photorefractive keratectomy (PRK) for moderate myopia using a solid-state laser with a wavelength of 213 nm alters the corneal endothelial cell density. SETTING University refractive surgery center. METHODS The corneal endothelium was analyzed preoperatively and 1, 6, and 12 months postoperatively using corneal confocal microscopy (modified HRT II with a Rostock ...

esults of excimer laser photorefractive kera-tectomy (PRK) for low and moderate myopia are clinically acceptable. 1,2 After PRK, slight changes in corneal transparency in the ablation zone or some superficial corneal problems can be observed postoperatively, no matter the excimer laser employed. Some reports describe anterior wound healing after excimer laser keratectomy. Tuft et al 3 and Marsh...