In order to test whether monounsaturated fatty acids (MUFA, M) would lower plasma cholesterol and/or triglycerides (E), 14 young men were studied in a metabolism ward. They were given two experimental diets with the same P/S ratio (P: polyunsaturated; S:saturated fatty acids) but different P + MIS ratios in composition of dietary fatty acids. Six men were in experiment I. In two groups of three...

Rosqvist, F. 2016. Dietary Fatty Acids, Body Composition and Ectopic Fat . Results from Overfeeding Studies in Humans. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1358. 94 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9523-7. The aim of this thesis was to investigate the effects of dietary fatty acids on body composition and ectopic fat i...

BACKGROUND A cornerstone of conventional dietary advice is the recommendation to replace saturated fatty acids (SFA) with mostly n-6 polyunsaturated fatty acids (PUFA) to reduce the risk of coronary heart disease (CHD). Many clinical trials aimed to test this advice and have had their results pooled in several meta-analyses. However, earlier meta-analyses did not sufficiently account for major ...

Heart-healthy dietary recommendations include decreasing the intake of saturated fatty acids (SFA). However, the relative benefit of replacing SFA with monounsaturated fatty acids (MUFA), polyunsaturated fatty acids (PUFA), or carbohydrates (CARB) is still being debated. We have used two mouse models of atherosclerosis, low density lipoprotein receptor-deficient (LDLRKO) and apolipoprotein E-de...

BACKGROUND As high dietary n-6 polyunsaturated fatty acids and n-6:n-3 PUFA ratio may contribute to many western ailments, increasing n-3 PUFA in foods could be beneficial. The nutritional significance of n-3 PUFA-fortified egg vs. enzymatically competitive high n-6 PUFA diets is debatable. OBJECTIVES To evaluate the dietary contribution of 'field fortification' of eggs by adding n-3 PUFA to ...

Corresponding author: Bo Kyung Koo https://orcid.org/0000-0002-6489-2656 Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul National University College of Medicine, 20 Boramae-ro 5-gil, Dongjak-gu, Seoul 07061, Korea E-mail: [email protected] Jang et al. [1] reported that high saturated fatty acid (SFA) or n-3 polyunsatura...

Routine use of parenteral lipid emulsions (LE) in clinical practice began in 1961, with the development of soybean oil (SO) - based LE. Although clinically safe, experimental reports indicated that SO-based LE could exert a negative influence on immunological functions. Those findings were related to its absolute and relative excess of omega-6 polyunsaturated fatty acids (PUFA) and the low amou...

Marine fish are high in essential omega-3 fatty acids, which important for human health. This study evaluated the effects of four extraction methods (soxhlet extraction, SE; wet rendering, WR; acid silage, AS; microwave-assisted MAE) on oil yield, physicochemical properties, profile, and nutritional quality index (NQI) pangus oil. The yield ranged from 13.50% to 21.80%, with MAE having highest ...

Whether the content of saturated (SFA), monounsaturated (MUFA), and polyunsaturated fatty acids (PUFA) could differently influence postprandial triglycerides (TG) is unknown. We examined possible differences in the postprandial TG response to fat tolerance tests (FTTs), in which SFA or unsaturated fatty acids were used. Crossover clinical trials investigating the effects of FTTs containing SFA ...