it is sometimes difficult to recognize a jaw lesion as osteosarcoma, ossifying fibroma or ‎fibrous dysplasia in routine hematoxylin and ‎eosin staining and a more accurate technique is needed to differentiate these ‎lesions. ‎many studies have shown the potential usefulness of silver-stained nucleolar organizer region (agnor) parameters for the diagnosis of various neoplasms. this study was car...

PURPOSE To investigate the potential antiproliferative effect of cyclin-dependent kinase inhibitor 1B (CDKN1B) overexpression in a rabbit model of glaucoma filtration surgery (GFS). METHODS The recombinant adenovector expressing exogenous CDKN1B was delivered to Tenon's capsule by subconjunctival injection during unilateral filtration surgery. The time course of CDKN1B expression was monitore...

Objective: This study is planned to evaluate the histological lesions of prostatic specimens and it’s correlation with the clinical data.Materials and Methods: The present study is a prospective study, undertaken in the Department of Pathology, Mahatma Gandhi Medical College, Jaipur, Rajasthan, during the period of July 2010 to May 2012. This study was conducted on 100 prostatic specimens refer...

Cavia tschudii Fitzinger, 1867 is a wild guinea pig species living in South America that according to the analysis of mitochondrial genes is the closest wild form of the domestic guinea pig. To investigate the genetic divergence between the wild and domestic species of guinea pigs from a cytogenetic perspective, we characterized and compared the C, G and AgNOR banded karyotypes of molecularly i...

In this study, quantitative DNA estimation (DNA ploidy), AgNORs and koilocytotic changes were assessed in oral leukoplakia for risk categorization. Materials and methods: 50 cases of oral leukoplakias along with adequate controls were selected for the study. Quantitative DNA analysis was done by FACS scan. AgNORs were studied by silver staining method, koilocytotic changes and histopathology we...

Tissue markers of cellular proliferatian have been recently utilized as prognostic indicators in brain tumors. Nudeolar organizer regions (NORs)are loops of deoxyribonudeic add (DNA) that transcribe to ribosomal ribonudeic acid (RNA) by RNA polymerase i. Using asilver staining technique. nudeolar organizer region-assodated proteins (AgNORs) have been studied in paraffin sections of 62 meningeal...

A study was undertaken to evaluate the Nucleolar organizing regions (NOR) count and histopathological changes in rat’s liver treated with methotrexate (MTX). Male Wistar rats aged 4 months, maintained in our institution were used in the present study. Animals were injected intraperitonealy with 3 different doses of methotrexate on alternative days for one week and the animals were sacrifi...

a study was undertaken to evaluate the nucleolar organizing regions (nor) count and histopathological changes in rat’s liver treated with methotrexate (mtx). male wistar rats aged 4 months, maintained in our institution were used in the present study. animals were injected intraperitonealy with 3 different doses of methotrexate on alternative days for one week and the animals were sacrificed on...