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Aberrant methylation has been shown to trigger the inactivation of tumor suppressor genes during tumorigenesis. MicroRNAs (miRNAs) have been found deregulated in human colorectal cancer (CRC), and some of them may function as tumor suppressor genes. Here, we investigated CpG island promoter hypermethylation as a potential mechanism underlying miRNA disruption and identifed methylation-sensitive...
to investigate the effects of deficit irrigation and different levels of nitrogen fertilizer on somequantitative and qualitative properties of melissa, a pot experiment was conducted for one year (2011) inmazandaran province. experiment was carried out as a factorial based on randomized complete blockdesign with three replications. irrigation treatments (25, 52 and 75 percent field capacity, fc...
Solid propellant systems are basically two types: case bonded and cartridge. Liner, a polymeric glue, is responsible for bonding propellant to casing in case bonded ones. Therefore, it must have sufficient mechanical and adhesive strength. The type and amount of each component of polymeric composition plays an important role in liner strength. In this research, effect of chain extender content ...
Objectives: (i) To expose ‘normal sleepers’ to a thirty two hour sleep deprivation protocol and evaluate the impact of this deprivation on a complex performance task i.e. The Paced Auditory Serial Addition Test (PASAT), (ii) To compare these sleep deprivation performance findings with historical data on the impact of sleepiness secondary to narcolepsy on PASAT performance measures, (iii) To inv...
Results: Maximum oxygen uptake was significantly correlated with 6 minute walking distance. Both exercise tests were correlated with pulmonary function tests. However, maximum exercise capacity was more closely correlated with measures of lung function than 6MWT. Both tests were significantly correlated with static lung volumes. Inspiratory capacity (IC) was significantly correlated with 6MWT a...
to study the effect of powdery mildew on sugar beet yield and percentage of sugar losses sugar percent losses, ten genotypes were compared in a factorial experiment based on randomized complete block design with 3 replications and two factors. the first factor was spraying treatment with two levels and the second were genotypes. inoculation was carried out using the pathogens' conidial ...
An experiment was performed to examine the effect of methyl jasmonate foliar spray with concentrations (10, 1, 0.1 mM and 0) and titanium nanoparticles with concentrations (40, 30, 20 µM and 0) on the physiological indices of Savory. The field experiment was carried out in Isfahan in the summer of 2019. This experiment was conducted in a factorial manner based on completely randomized design a...
BACKGROUND Having a child with Down syndrome (DS) is usually unexpected and stressful. AIM To describe the experiences of parents of children with DS at the time of diagnosis. MATERIAL AND METHODS A self-administered survey was answered by 345 parents (62% women) with an offspring with DS. RESULTS Eighty four percent of parents received a postnatal diagnosis of DS, 32.3% were informed of ...
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