Transforming growth factor-β (TGF-β) proteins are important cytokines in the occurrence and development of tumors. However, its neural functions in glioma are still not understood. In the present study, we evaluated the effects of TGF-β1 on glioma cell line U87. miR-205 and miR-195 were involved in TGF-β1 signaling pathway. Quantitative real-time PCR was used to detect miR-205 and miR-195 level...

This article investigates the application of swarm and evolutionary algorithms, namely SOMA, DE, GA, for optimizing F-transform-based image compression. To do this, we introduce cost function, evaluating approximation decompressed to original image, concerning parameters that control quality F-transform. function is then minimized by selected algorithms find optimal settings compression decompr...

MicroRNAs (miRNAs) are endogenously small non-coding RNAs which are key post-transcriptional regulators of gene expression. Deregulation of miRNAs is common in human tumorigenesis. We report that miRNA-205 is significantly down-regulated in glioma cell lines and tissue specimens. Ectopic expression of miRNA-205 induces apoptosis, cell cycle arrest...

BACKGROUND AND AIM: It is required in many young patients that permanent first molars (PFMs) be extracted due to poor prognosis. This study investigates whether the extraction of such teeth is effective on the development of third molars and even their crown and root morphologies.METHODS: A total of 7000 panoramic radiographs were evaluated and 128 radiographs showing a history of extraction of...

AIMS To investigate the impact of iron intake on the development of type 1 diabetes (T1DM). METHODS Case-control study with self-administered questionnaire among families of children with T1DM who were less than 10 years old at the time of the survey and developed diabetes between age 1 and 6 years. Data on the types of infant feeding in the first 4 months of life was collected from parents o...

Introduction: Human Cytomegalovirus (HCMV) or Human Herpes Virus Type-5(HHV-5) is a member of herpesviridae placed in subtype beta herpesvirinae. CMV is a ubiquitous pathogenic virus and can infect humans all through their life. Prevalence of CMV infection in developed countries is about 45% and in developing countries it varies up to 100%. CMV infection during pregnancy is very important, beca...

sleep plays a vital role in regulating physiological mechanisms in the human body. nowadays, by the change of lifestyle and as a consequence of longer work hours and increased accessibility to media, sleep disturbance becomes a common problem in modern society. many studies demonstrated that sleep disturbance triggers a systemic low-grade inflammation by increasing the level of several cytokine...