Mitochondrial dysfunction and endoplasmic reticulum (ER) stress are closely associated with β-cell dysfunction and peripheral insulin resistance. Thus, each of these factors contributes to the development of type 2 diabetes mellitus (DM). The accumulated evidence reveals structural and functional communications between mitochondria and the ER. It is now well established that ER stress causes ap...

Mental health problems among children are on the rise across United Kingdom. Teachers uniquely placed to play a vital role in early identification and intervention. This study aims identify discuss potential barriers Scottish teachers' concerning their supporting children's mental health. One hundred seventy-nine primary school teaching staff from 30 different council areas completed an online ...

Background: Iran has experienced a great variation in women status in recent years. There is a little information on how and why advancing gender equality and equity and the empowerment of women play a role in recent fertility reduction in the country. This study was conducted to gain an insight into the role of gender beliefs and women empowerment in couples’ experiences of fertility in Mashha...

Localization systems are an important component of Ambient and Assisted Living platforms supporting persons with cognitive impairments. The paper presents a positioning system being part the platform developed within IONIS European project. system’s main function is providing data on user mobility localization, which would be used to analyze his/her behavior detect dementia wandering symptoms. ...

Inhibition of matrix-metalloproteinases (MMPs) by tissue inhibitors of metalloproteinases (TIMPs) has been shown in vivo to decrease metastasis and tumor-associated angiogenesis. Our laboratory is interested in understanding the role of these proteins at the pericellular microenvironment of tumor and endothelial cells. Secretion of MMPs by tumor cells enables the migration, invasion and metasta...