Eleven conjugates between dihydroartemisinin (DHA) with thiols containing both ether and thioether bonds were designed, synthesized by a two-step procedure including etherification S-alkylation. Analysis of the NMR spectral data indicated that dimer DHA 6-mercaptopurine 2-mercaptoimidazole was produced yields 31% 62%, respectively. Furthermore, tautomerization thiol 5-methoxy-2-mercaptobenzimid...