The present study describes the pharmacological profile of ((E)-alpha-[[1-butyl-5-[2-[(2-carboxyphenyl)methoxy]-4-methoxy-phenyl ]-1H-pyrazol-4-yl]methlene]-6-methoxy-1,3-benzodioxole-5-propanoic acid) (SB 234551), a high-affinity, nonpeptide endothelin type A (ETA)-selective receptor antagonist. In human cloned ETA and endothelin type B (ETB) receptors, SB 234551 produced a concentration-depen...

background: aflatoxin-contaminated feed cause mortality, suppression of the immune system, reduced growth rates and losses in feed efficiency. an experiment was conducted to evaluate the ability of different levels of sodium bentonite (sb), silybummarianum seeds (sms) and their combination for reducing the adverse effects of aflatoxin b1 (afb1) in broiler chicks. materials and methods: 224 male...

MSK1 (mitogen- and stress-activated kinase 1) and MSK2 are nuclear protein kinases that regulate transcription downstream of the ERK1/2 (extracellular-signal-regulated kinase 1/2) and p38α MAPKs (mitogen-activated protein kinases) via the phosphorylation of CREB (cAMP-response-element-binding protein) and histone H3. Previous studies on the function of MSKs have used two inhibitors, H89 and Ro ...

studies have shown that aflatoxin is immunosuppressive and its ingestion in feed has resulted in decreased immunity in vaccinated birds .therefore, the purpose of the present study was to determine the efficacy of sodium bentonite (sb) and esterified glucomannan (e-gm) of yeast cell wall, in counteracting the toxic effects of aflatoxin (af) on immunization against infectious bursal disease (ibd...

A provisional, single-stent strategy is currently regarded as the default strategy for the treatment of bifurcation lesions, because of beneficial outcomes associated with this technique (1,2). However, this approach cannot be applied broadly across all bifurcation lesions because of the likelihood of side branch (SB) compromise in the presence of high-risk features (e.g. significant SB ostial ...

BACKGROUND Health effects of sedentary behaviors (SB) may vary depending on their characteristics such as type, purpose, duration, and intensity of the behavior. While a growing number of questionnaires assess sedentary behaviors, it is unclear which characteristics of SB are measured. The aim of this review was to examine the content of self-report SB questionnaires. METHODS Three databases ...

Although native bismuth is a relatively common mineral, native antimony is less abundant, and Sb-Bi alloys are relatively rare phases in Nature. Sb-Bi alloys and Ag-Cu-Pb-Sb-Bi sulphosalts have been discovered in the Jialong vein-type Cu-Sn deposit in North Guangxi, South China. The Jialong deposit is hosted by schist within the contact zone of a Neoproterozoic granite. Four stages of ore forma...