Polydimethylsiloxane (PDMS) is the most popular and versatile material for soft lithography due to its flexibility and easy fabrication by molding process. However, for nanoscale patterns, it is challenging to fill uncured PDMS into the holes or trenches on the master mold that is coated with a silane anti-adhesion layer needed for clean demolding. PDMS filling was previously found to be facili...

Material surface topography is an important factor for regulating cellular behaviour. Understanding the mechanism of how surface topography influences mammalian cells is critical for the development of medical implants and tissue engineering. In this study, we investigated the influences of nanoporous and microgrooved substrates on the morphology and migration of hepatic cell line, BEL-7402 cel...

This paper describes a simple method for fabricating a variable-focus lens by using PDMS (polydimethylsiloxane) and filling with liquid for the variable-focus lens. The lens diameter of 2-mm was designed in this experiment and expected to reach the focal length in the range of 3 ~ 12 mm. The theoretical value between the liquid volume and the lens contact angle at different focal lengths were s...

Polymers that respond in a productive fashion to their environment are under active development as they offer significant advantages over traditional materials. For example, polymers with the ability to self-heal and recover a significant fraction of their initial properties after being subjected to a damage event are of significant interest. Here we study the effect of healing agent viscosity ...

The vast majority of droplet-based microfluidic devices are made from polydimethylsiloxane (PDMS). Unfortunately PDMS is not suitable for high frequency droplet generation at high operating pressure due to its low shear modulus. In this paper, we report the fabrication and testing of microfluidic devices using thermoset polyester (TPE). The optical characteristics of the fabricated devices were...

Objectives: The aim of this study was to compare the fine motor development between Low Birth Weight (LBW) infants and Normal Birth Weight infants (NBW) at the age of 8-12 months by using the Peabody Developmental Motor Scale-2 (PDMS-2) . Methods: This was a non experimental and cross sectional study which was conducted on the 18 LBW infants and 14 normal infants. By referring to the profile...

This paper demonstrates a new method of implementing complex microchannels in PDMS, which is simply constructed using three-dimensional photoresist structures as a master mold for the PDMS replica process. The process utilizes UV-insensitive LOR resist as a sacrificial layer to levitate the structural photoresist. In addition, the thickness of photoresist structures can be controlled by multi-s...

This paper reports the use of a recent composite material, i-PDMS, made of carbonyl iron microparticles mixed in a PolyDiMethylSiloxane (PDMS) matrix, for magnetophoretic functions such as capture and separation. Indeed, we demonstrated that this composite can locally generate high magnetic field gradients when placed between two permanent magnets. We first investigated the molding resolution o...

We have developed a fluorescence-based microfluidic system for high-throughput analyses of the function of ATPbinding cassette (ABC) transporters. Our device consists of polydimethylsiloxane (PDMS) and a glass that tethers vesicles on its surface. Although PDMS is a great material for fabrication of microfluidic channels, it absorbs fluorescent molecules and hampers quantitive fluorescence anal...

We explored the use of soft and flexible graphene (Gr)-reinforced polydimethylsiloxane (PDMS; Gr-PDMS) Gr-carbon nanotube (CNT)-reinforced PDMS (Gr-CNT-PDMS) as nanocomposites (NCPs) in wearable electronic applications investigated their mechanical electrical properties. Specifically, we evaluated reinforcement NCPs by performing Shore scleroscope hardness machine-washing tests properties using...