Treatment of 1,3-bis(3'-butylimidazolyl-1'-yl)benzene diiodide with elemental sulfur in the presence of a base produced a bis(N-heterocyclic thione) (NHT) pincer ligand precursor. Its reaction with PdCl2(CH3CN)2 produced chloro[1,3-bis(3'-butylimidazole-2'-thione-κ-S)benzene-κ-C]palladium(ii), a 6,6-fused ring SCS-NHT palladium pincer complex. This air stable compound is, to our knowledge, the ...

Novel 3-(3-benzyl-2,3-dihydrobenzo[ d]thiazol-2-yl)benzo[ d]oxazole-2(3 H)-thione derivatives are efficiently synthesized in excellent yields by reactions of benzothiazoles, benzyl bromides, and 2-mercaptobenzoxazole acetone under catalyst-free conditions the presence triethylamine. The structures products confirmed nuclear magnetic resonance spectroscopy, infrared electron ionization mass spec...

In order to determine the optimum size of heterocycle of lead compound 1 (6-methyl-3-phenethyl-3,4-dihydro-1H-quinoline-2-thione; IC(50)=0.8 microM) for inhibition of melanogenesis, we have synthesized and evaluated some benzimdazole-2(3H)-thiones 5a-e. The preliminary bioassay has shown that the benzimdazole-2(3H)-thione motif of 5 is essential structural unit for their inhibitory activity. Am...

Reactions of copper(I) halides with imidazolidine-2-thione and 1-methyl-1,3-imidazoline-2-thione in dmso involved C-S rupture in aerobic conditions and yielded a sulfate bridged polymer, [Cu(II){eta(2)-N,N-(N(2)C(3)H(5))(2)S}(mu-O,OSO(2))(eta(1)-OH(2))](n) 1 and a sulfate chelated monomer, [Cu(II){eta(2)-N,N-(N(2)C(4)H(5))(2)S}(eta(2)-O,OSO(2))(eta(1)-OH(2))] 2 {N,N-(N(2)C(3)H(5))(2)S = 2,2'-th...

Three diazoles namely 5-methyl-1,3,4-oxadiazole -2(3H)-thione, 5-methyl-1,3,4-thiadiazol-2(3H)-thione and 4-amino-5-methyl-2H-1,2,4-triazole-3-thiol were synthesized from acetic acid or ethyl acetate. Seco-acyclo-N-nucleoside analogous was by condensation of 1,3-benzylidine-glyceryl-2-tosylate with the three diazoles. Structural proof based upon IR, 1H-NMR, 13C-NMR spectroscopy MS measurements....

Two selenated analogues of the all-sulfur single-component molecular conductor [Ni(Et-thiazdt)2] (Et-thiazdt = N-ethylthiazoline-2-thione-4,5-dithiolate) have been prepared from their precursor radical-anion complexes. Replacement thione by a selenone moiety gives neutral [Ni(Et-thiazSedt)2] complex. It adopts an unprecedented solid-state organization (for nickel complexes), with formation perf...

As a continuation of our efforts in developing new antimycobacterial agents, a series of new 1,3-thiazolidine-2-thione derivatives were synthesized. The chemical structures of the compounds were elucidated by FT-IR, 1H-NMR and Mass spectra. The analysis of theoretical toxicity risks,drug-likeness and drug-score for these series using Osiris program showed acceptable results.

In the title compound, [Cu(3)I(3)(C(5)H(5)NS)(3)](n), a polymeric structure is formed along [100] through bridging iodide and pyridine-2-thione ligands. The metal atoms are engaged in [Cu(3)S(3)] and [Cu(2)S(2)] rings sharing Cu-S edges, with the [Cu(2)S(2)] rings located about inversion centers. Cu(I) atoms bridged by iodide ions exhibit the shortest Cu⋯Cu separation in the polymer [2.8590 (14...