نتایج جستجو برای: 2 3 indolyl 45 di phynyl imidazoleidpi
تعداد نتایج: 3642027 فیلتر نتایج به سال:
N-Indolyl or N-benzofuranyl indoles and benzimidazoles were prepared through metal-catalyzed tandem reactions between 2-alkynyl cyclohexadienimines or cyclohexadienones and 2-alkynylanilines or N(1)-benzylbenzene-1,2-diamine.
Nerve growth factor-induced B (NGFI-B) genes are orphan nuclear receptors, and NGFI-B alpha (Nur77, TR3) is overexpressed in bladder tumors and bladder cancer cells compared with nontumorous bladder tissue. 1,1-Bis(3'-indolyl)-1-(p-methoxyphenyl)-methane (DIM-C-pPhOCH(3)) and 1,1-bis(3'-indolyl)-1-(p-phenyl)methane have previously been identified as activators of Nur77, and both compounds inhib...
An improved and practical synthesis of substituted quinolines and bis(indolyl)methanes was achieved under microwave condition using Zn(OTf)(2) as catalyst. The synthesized compounds have been screened for antimicrobial and antioxidant activities.
The C−F bond activation of pentafluoropyridine and 2,3,5,6-tetrafluoropyridine at [Ni(cod)2] (cod=1,5-cyclooctadiene) in the presence phosphine PPh2(Ind) (Ind=3-methyl-2-indolyl) led to formation nickel(II) fluorido bis(phosphine) complexes trans-[Ni(F)(2-C5NF4){PPh2(Ind)}2] trans-[Ni(F)(2-C5HNF3){PPh2(Ind)}2]. are characterized by intramolecular hydrogen bonds between NH group ligands ligand. ...
Newly synthesized 2-(2-((1H-indol-5yl)methylene)-hydrazinyl)-thiazole derivatives were evaluated for their in vitro cytotoxicity on two carcinoma cell lines A2780 and HeLa. Significant cytotoxic activity for 2-(2-((1H-indol-5-yl)methylene)hydrazinyl)-4-methylthiazole (1) and 2-(2-((1H-indol-5-yl)methylene)hydrazinyl)-4-phenylthiazole (3), on both A2780 [IC50: 11.6 μM (1), and 12.4 μM (3)] and H...
1-Carboxymethyl-3-methylimidazolium chloride {[cmmim]Cl} is utilized as a highly efficient and reusable catalyst for the synthesis of bis(indolyl)methanes by the condensation reaction of indole with arylaldehydes under solvent-free conditions at room temperature. In summary, the presented method have several advantages including simplicity, low cost, generality, efficiency, clean reaction profi...
There is need to develop simple, efficient & economically viable chemical pathways to synthesise biologically active & commercially important heterocyclic Bis(indolyl) methanes1.The indole ring is an important constituent of many natural products, pharmaceuticals & other compounds of commercial importantance2. The literature survey shows that Bis(indolyl) methanes are know...
Two new long chain tryptophan compounds viz [3-(indolyl-30)-2-(N-octadecamido)]-methylpropionate (4) and sodium-[3-(indolyl-30)-2(N-octadecamido)]-propionate (5) have been prepared and their ̄uorescence properties ( max, f, f, rss, quenching) have been investigated in homogeneous media and in phosphatidyl choline vesicles. Both 4 and 5 in a membrane mimicking system of phosphatidylcholine vesic...
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