Heterozygous chromosomal inversions suppress recombination. Therefore, they may potentially influence recombination-associated phenotypes of human diseases, but no studies have verified this hypothesis. Here, we describe a 35-year-old man with severe congenital ichthyosis. Mutation analysis revealed a heterozygous splice-site mutation, c.1374-2A>G (p.Ser458Argfs*120), in KRT10 on 17q21.2. This ...

1374 www.thelancet.com Vol 387 April 2, 2016 be “the difference in home systolic blood pressure between each active drug (spironolactone, doxazosin, bisoprolol) and placebo”. The function and obligation of the SAP was to specify how the primary hypothesis would be addressed, using the prespecified primary outcome measures, capturing the maximum amount of information that has been discovered by ...

Starting from either the exchange or the exchange-correlation density together with Bader’s definition of an atom in a molecule, an atomic hole density function can be defined. Contour maps of atomic hole density functions are able to show how the electron density of each atom in a molecule is partially delocalized into the rest of atoms in the molecule. The degree of delocalization of the atom...

intake, physical activity, and population-wide weight loss on cardiovascular disease and diabetes mortality in Cuba, 1980–2005. Am J Epidemiol 2007;166:1374–80. 7 Rosenkilde M, Auerbach P, Reichkendler MH, Ploug T, Stallknecht BM, Sjodin A. Body fat loss and compensatory mechanisms in response to different doses of aerobic exercise – a randomized controlled trial in overweight sedentary males. ...

Evidence supporting nitric oxide (NO) as a mediator of plant biochemistry continues to grow, but its functions at the molecular level remains poorly understood and, in some cases, controversial. To study the role of NO at the transcriptional level in Betula platyphylla cells, we conducted a genome-scale transcriptome analysis of these cells. The transcriptome of untreated birch cells and those ...

In order to understand the ecological impact of rehabilitation Félix Houphouët-Boigny University Campus on bird community, a study was carried out over two months (October-November 2016). The ornithological inventory by IPA method in five different habitats identified campus gave total species richness 51 41 genera, 27 families and 13 orders for 1374 birds, with H' = 2.93 J 0.74. Five dominate ...