Abstract Background The proprotein convertase subtilisin/kexin type 9 (PCSK9) is a novel cardiovascular risk factor. Levels of PCSK9 in thrombotic primary antiphospholipid syndrome (PAPS) have never been investigated. Methods Cross sectional comparison baseline characteristics 91 PAPS patients enrolled the multicenter ATHERO-APS cohort study. levels were categorized into tertiles and associatio...

Queen Helen Nemanjić (?–Brnjaci near Zubin Potok, February 8, 1314) was a Serbian medieval queen and consort of King Stefan Uroš I (r. 1243–1276), the fifth ruler Nemanide dynasty. She mother kings Dragutin II Milutin. Today, she is known as Anjou (Jelena Anžujska in Serbian) although her real name most probably Heleni Angelina (Ελένη Aγγελίνα). founder Orthodox monastery Gradac well four Franc...

We present allesfitter, a public and open-source python software for flexible robust inference of stars exoplanets given photometric radial velocity data. Allesfitter offers rich selection orbital transit/eclipse models, accommodating multiple exoplanets, multi-star systems, transit-timing variations, phase curves, stellar variability, star spots, flares, various systematic noise models includi...

Formal Darwinism (FD) [Grafen (2002) J Theor Biol 217:75–91; (2007) Evol 20:1243–1254.] is a theoretical framework for articulating optimization models in behavioral ecology and allele dynamics modeling population genetics. It yields teleology centered on inclusive fitness maximization (“IF teleology”), which captures the many aspects of Darwinian thinking [Huneman (2019b) Stud Hist Philos Sci ...

BACKGROUND Green tea catechins (GTCs) with or without caffeine have been studied in randomized controlled trials (RCTs) for their effect on anthropometric measures and have yielded conflicting results. OBJECTIVE The objective was to perform a systematic review and meta-analysis of RCTs of GTCs on anthropometric variables, including body mass index (BMI), body weight, waist circumference (WC),...

A 42-year-old man was diagnosed with a severe acute respiratory distress syndrome following inhalation of his stomach contents. The previous history revealed liver cirrhosis due to alcoholic liver disease. Seven days later, he presented with a high fever and a painful abdominal distension due to ascites. The blood cell count was as follows: hemoglobin, 10.9 g/dL; white blood cells, 12.2303 10/L...

BACKGROUND Population surveys are frequently used to assess prevalence, correlates and health benefits of physical activity. However, nonsampling errors, such as question order effects, in surveys may lead to imprecision in self reported physical activity. This study examined the impact of modified question order in a commonly used physical activity questionnaire on the prevalence of sufficient...