OBJECTIVE To assess the association between use of macrolide antibiotics in mothers and infants from pregnancy onset until 120 days after birth and infantile hypertrophic pyloric stenosis (IHPS). DESIGN Nationwide register based cohort study. SETTING Denmark, 1996-2011. PARTICIPANTS 999,378 liveborn singletons and linked individual level information on macrolide prescriptions (maternal us...

OBJECTIVES The aim of our study was to investigate early mortality after cardiac surgery and to determine the most adequate follow-up period for the evaluation of mortality rates. METHODS Information on all adult cardiac surgery procedures in 10 of 16 cardiothoracic centres in Netherlands from 2007 until 2010 was extracted from the database of Netherlands Association for Cardio-Thoracic Surge...

Peritonitis is a major complication of peritoneal dialysis, but the relationship between peritonitis and mortality among these patients is not well understood. In this case-crossover study, we included the 1316 patients who received peritoneal dialysis in Australia and New Zealand from May 2004 through December 2009 and either died on peritoneal dialysis or within 30 days of transfer to hemodia...

The hemodynamic alterations associated with the developmental phase of high blood pressure were investigated in the spontaneously hypertensive rat (SHR). All hemodynamic measurements were made in unanesthetized, unrestrained SHR and Wistar-Kyoto (WKY) rats instrumented with chronic electromagnetic flow probes on the ascending aorta and arterial pressure catheters. Rats were studied at 30-41 day...

1. Heart and liver tissue samples were obtained from rats in various developmental stages from the 12-day-old embryo to the 120-day-old postnatal animal. 2. The body, heart and liver weights and percentage protein in the liver and heart of the prenatal and postnatal rat were determined. 3. The activities of NADH-, NADPH- and succinate-cytochrome c reductases and cytochrome oxidase were determin...

The objectives were to assess incidence of pregnancy losses, associate this outcome with immunization programs against reproductive diseases, and evaluate the effects of vaccination against bovine herpesvirus-1 (BoHV-1), bovine viral diarrhea virus (BVDV), and Leptospira spp., on reproductive efficiency of Brazilian cow-calf operations. In experiment 1, 7614 lactating Nelore cows from 18 ranche...

Identifying species or individuals that feed upon other species of animals is an important aspect of some predation studies. We evaluated the effectiveness with which the biomark associated with iophenoxic acid (IA) injections was transferred from domestic goats to coyotes (Canis latrans) that fed on them. We injected doses of 100, 300, or 1,000 mg of IA into goats to raise serum iodine levels,...

Background: One of the basic principles for treatment COVID-19 patients is early initiation etiotropic therapy. The evidence base assessment efficacy and safety antivirals continues to expand with new clinical trials. promising medications molnupiravir.
 Aim: To evaluate molnupiravir (Esperavir) in outpatients COVID-19.
 Materials methods: This randomized comparative open-label study ...

Species of tapeworms belonging to the family Taenidae are among the most important helminth parasites of man and domestic animals. Taeniasis and cysticercosis are serious problems of public health and economy in developing countries. The ultimate control of these diseases depends on the development of effective prophylactic vaccines. Although vaccines against bacterial and viral infections are ...

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