BACKGROUND In this study we investigated changes in the status of antibiotic use in Tianjin since the implementation of the Antibiotic Stewardship Program (ASP) (2011-2013), as well as existing problems, strategies, and outcomes to promote rational clinical antibiotic use. MATERIAL AND METHODS A quasi-experimental study was performed to investigate situations of antibiotic use in secondary and ...

Environmental pollution with heavy metals is a global disaster that is related tohuman activities. This study was conducted to determine the extent of heavy metalsaccumulation by plant species in Lia industrial city (Qazvin, Iran) and to investigate theremediative capacity of native plant species grown in the contaminated soils. Soil andindustrial wastewater sampling was done radially along tra...

background research to understand and control the emergence and spread of antimicrobial resistance has become a public health priority. objectives this study was conducted to study epidemiology and resistant pattern of bacteria causing infection in different king khalid hospital units. patients and methods all samples were sent to the lab and routinely processed according to the standard microb...

environmental pollution with heavy metals is a global disaster that is related tohuman activities. this study was conducted to determine the extent of heavy metalsaccumulation by plant species in lia industrial city (qazvin, iran) and to investigate theremediative capacity of native plant species grown in the contaminated soils. soil andindustrial wastewater sampling was done radially along tra...

OBJECTIVE To implement and evaluate the effect of a computerized decision support tool on antibiotic use in an intensive care unit (ICU). DESIGN Prospective before-and-after cohort study. SETTING Twenty-four bed tertiary hospital adult medical/surgical ICU. PARTICIPANTS All consecutive patients from May 2001 to November 2001 (N = 524) and March 2002 to September 2002 (N = 536). INTERVEN...

BACKGROUND High levels of multidrug resistance are usually associated with mobile genetic elements that encode specific resistance genes. Integrons are important genetic elements involved in spreading antibiotic multi-resistance. In special cases, large exogenous segments in bacterial genomes form genomic islands, and one of the functions of these genomic islands is antibiotic resistance. Due t...

Traditional antibiotic dosing was not designed for today's escalating antibiotic resistance, lack of novel antibiotics and growing complexity in patient populations. Dosing that ensures optimal antibiotic exposures should be considered essential to increase the likelihood of effective patient treatment. Given the variability in these exposures across different patients, a 'one-dose-fits-all' ap...

Ethnobotanical surveys of Cerrado native plants show that leaves of Celtis iguanaea (Jacq.) Sargent (Cannabaceae), popularly known in Brazil as "esporão de galo", are used in folk medicine for body pain, asthma, cramps, poor digestion, urinary infection, kidney dysfunctions, as well as a stimulant and diuretic. This work aimed at evaluating possible C. iguanaea aqueous leaf extract (CALE) cytot...

Pseudomonas species are opportunistic pathogens with implications in a wide range of diseases including cystic fibrosis and sickle cell anaemia. Because of their status as multidrug resistant (MDR) and extremely drug resistant (XDR) bacteria Pseudomonas species represent a threat to public health. Prevalence, antibiogram and associated antibiotic resistant genes of Pseudomonas species isolated ...