Let p be an odd prime. Define en = { (−1), if n is a quadratic residue mod p, (−1)n+n+1, if n is a quadratic nonresidue mod p, where n is the multiplicative inverse of n modulo p such that 1 ≤ n ≤ p − 1. This paper shows that the sequence {en} is a “good” pseudorandom sequence, by using the properties of exponential sums, character sums, Kloosterman sums and mean value theorems of Dirichlet L-f...

A prime number p is called b-elite if only finitely many generalized Fermat numbers Fb,n = b 2 + 1 are quadratic residues modulo p. Let p be a prime. Write p − 1 = 2h with r ≥ 0 and h odd. Define the length of the b-Fermat period of p to be the minimal natural number L such that Fb,r+L ≡ Fb,r (mod p). Recently Müller and Reinhart derived three conjectures on b-elite primes, two of them being th...

SR-BI deficient mice that are also hypomorphic for apolipoprotein E expression develop diet induced occlusive coronary artery atherosclerosis, myocardial infarction and early death. To test the role of SR-BI in bone marrow derived cells, we used bone marrow transplantation to generate SR-BI-null; apoE-hypomorphic mice in which SR-BI expression was restored solely in bone marrow derived cells. S...

Reaction of 5S RNA with chlorocetaldehyde leads to the conversion of unpaired adenines to the fluorescent 1,N6-etheno-adenine derivatives. Up to 16 of the 23 adenines in free 5S RNA can be modified, the fastest reacting are A29, A34, A57-59. Partial modification of adenines in this area results in a 20% reduction in the efficiency of 5S RNA incorporation into 50S subunits during reconstitution ...

It is based on the intractability of Quadratic Residuosity Assumption modulo a composite N . Very roughly, we select uniformly at random Quadratic Residues from ZN to encrypt 0 bit and to encrypt 1 bit we select quadratic non-residue from ZN . However, since the distribution of quadratic residues and quadratic non-residues are not same in ZN we confine ourselves to a subset of ZN where the numb...

Scavenger receptor class B type I (SR-BI) is an HDL receptor that promotes bidirectional fl ux of free cholesterol between cells and HDL, as well as selective uptake of HDL cholesteryl ester into hepatocytes and steroidogenic cells ( 1, 2 ). Single deletion of mouse SR-BI accelerates atherosclerosis, whereas combined deletion of SR-BI and ApoE mimics several features of human coronary disease, ...

Protein translocation across and insertion into membranes is a process essential to all life forms. In higher eukaryotes, this process is initiated by targeting the translating ribosome to the endoplasmic reticulum via the signal recognition particle (SRP) and its membrane-associated heterodimeric receptor (SR). This targeting step is regulated by three G proteins, SRP54, SR alpha, and SR beta,...

Title of Document: CHARACTERIZATION OF ARABIDOPSIS THALIANA SR PROTEIN GENES: MUTATIONS, ALTERNATIVE SPLICING, AND ESE SELECTION. Jason Edmonds, Doctor of Philosophy, 2007 Directed By: Associate Professor, Stephen M Mount, Department of Cell Biology and Molecular Genetics RNA processing in eukaryotes is a highly complex process requiring numerous steps and factors that can play roles in the reg...

OBJECTIVE The antioxidant properties of high-density lipoprotein (HDL) have been attributed to paraoxonase (PON) enzyme activity. Human scavenger receptor class B type 1 (SR-BI; CD36 and lysosomal integral membrane protein-II analogous-1 [CLA-1]) plays a central role in HDL-mediated native and oxidized cholesteryl ester uptake. We tested for a significant contribution of common variant of these...

HCV entry into cells is a multi-step and slow process. It is believed that the initial capture of HCV particles by glycosaminoglycans and/or lipoprotein receptors is followed by coordinated interactions with the scavenger receptor class B type I (SR-BI), a major receptor of high-density lipoprotein (HDL), the CD81 tetraspanin, and the tight junction protein Claudin-1, ultimately leading to upta...