Eight new phenylisoxazole isoniazid derivatives, 3-(2′-fluorophenyl)isoxazole-5-carbaldehyde isonicotinylhydrazone (1), 3-(2′-methoxyphenyl)isoxazole-5-carbaldehyde (2), 3-(2′-chlorophenyl)isoxazole-5-carbaldehyde (3), 3-(3′-clorophenyl)isoxazole-5-carbaldehyde (4), 3-(4′-bromophenyl)isoxazole-5-carbaldehyde (5), 5-(4′-methoxiphenyl)isoxazole-3-carbaldehyde (6), 5-(4′-methylphenyl)isoxazole-3-c...

Background Infections can trigger worsening of atopic dermatitis (AD). Objectives To examine whether hospital-managed paediatric AD is associated with increased risk extracutaneous infections requiring hospitalization in childhood. Methods A nationwide-based cohort study using Danish registries was done. Children aged < 18 years a hospital diagnosis and children without were sex- age-matched at...

Background In the Netherlands, access to direct-acting antivirals (DAAs) against hepatitis C virus (HCV) has been unrestricted for chronic infection since 2015. We evaluated whether nationwide incidence of HCV infections in individuals with HIV changed Methods this retrospective cohort study, data from ATHENA people aged 18 years or older attending any 24 treatment centres Netherlands between 2...

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