We prove higher integrability and differentiability results for local minimizers u: R2 ⊃ Ω → RM , M ≥ 1, of the splitting-type energy Ω[h1(|∂1u|) + h2(|∂2u|)] dx. Here h1, h2 are rather general N -functions and no relation between h1 and h2 is required. The methods also apply to local minimizers u: R2 ⊃ Ω → R2 of the functional ∫ Ω[h1(|div u|) + h2(|ε(u)|)] dx so that we can include some varian...

To resolve the current ambiguity in the splitting function corresponding to the quark transversity distribution h1(x), we calculate h1(x) for a dressed quark in light-front Hamiltonian perturbation theory. Our result agrees with the expected form of the splitting function found in the literature and disagrees with the recent calculation in [1]. We emphasize the importance of quark mass in h1(x)...

In 2009 we reported that depletion of Dicer-1, the enzyme that catalyzes the final step of miRNA biosynthesis, prevents metamorphosis in Blattella germanica. However, the precise regulatory roles of miRNAs in the process have remained elusive. In the present work, we have observed that Dicer-1 depletion results in an increase of mRNA levels of Krüppel homolog 1 (Kr-h1), a juvenile hormone-depen...

The negative signal provided by interactions of programmed death-1 (PD-1) and its ligands, B7-H1 and B7-DC, has been suggested to play an important role in tumor evasion from host immunity. Pancreas cancer patients with B7-H1 expression have a poor prognosis. B7-H1 blocking has been shown to inhibit the development of a subcutaneous tumor from a pancreas cancer cell line. In this study, we inve...

Nucleoside diphosphate kinase (NDPK, Nm23), a housekeeping enzyme, is known to be a multifunctional protein, acting as a metastasis suppressor, transactivation activity on c-myc, and regulating endocytosis. The cellular mechanisms regulating Nm23 functions are poorly understood. In this study, we identified the modifications and interacting proteins of Nm23-H1 in response to oxidative stress. W...

At the initial phase of cell differentiation in mouse neuroblastoma (N18) induced by dibutyrylcyclic AMP (dbcAMP), an additional site of histone H1 was extensively phosphorylated. Forskolin and various phosphodiesterase inhibitors also induced both cell differentiation and H1 phosphorylation at the identical site. The phosphorylation preferentially occurred in a single H1 subtype (H1c) among th...

Definition 1 (Partition) A collection of sets {H1, . . . ,HK} is a partition of another set H if 1. the events are disjoint, which we write as Hi ∩Hj = ∅ for i 6= j; 2. the union of the sets is H, which we write as ∪k=1Hk = H. In the context of identifying which of several statements is true, if H is the set of all possible truths and {H1, . . . ,HK} is a partition of H, then exactly one out of...

Abstract Background To investigate the effects of chronic intrauterine hypoxia on insulin resistance, hypertension, and correlation between them in adult offspring rats. Methods A total 25 pregnant Sprague Dawley rats were randomly assigned into 4 prenatal (H) groups (10% ± 1% oxygen) a control group (21% oxygen). The H divided whole (1–21 day), early (1–7 mid (8–14 late (15–21 day) gestational...