Abstract Study question Is it possible to classify sperm morphology as normal or abnormal based on their kinetic characteristics? Summary answer Using different classifiers, was found that balanced dataset the classification scores of individual can be optimized during motility just before ICSI What is known already Sperm selection plays a crucial role ICSI. This by embryologists accompanied tw...

Ocular surface disease (OSD) is a common adverse event in dupilumab-treated patients with atopic dermatitis (AD). The pathomechanism remains unclear. At present, no data are available on dupilumab levels the eyes of these patients. aim this study to measure tear fluid after 4 and 28 weeks treatment. This prospective included moderate-to-severe AD Patients were seen by dermatologist an ophthalmo...

Background Antiretroviral therapy (ART) for HIV has significantly reduced morbidity and mortality, but the drugs can be expensive. This study aimed to estimate lifetime cost of management from Australian healthcare perspective. Methods A Markov cohort model, consisting 21 health states based on CD4 count line ART, simulated disease progression over persons living with HIV. We reported costs usi...