To elucidate the mechanisms by which the new bipyridine inotropic agent milrinone improves cardiac function, we examined multiple indexes of left ventricular diastolic function before and after administration of milrinone to patients with advanced (NYHA class III or IV) congestive heart failure. In 13 patients left ventricular pressure measurements were made with a micromanometer to permit asse...

Maximal and sphincter pressure was measured in 22 patients with spinal cord lesions and in a group of 10 controls, using perfused sleeve manometry. The mean resting pressure of the spinal patients was 63+/-8 (SEM) mm Hg, and of the control group 116+/-14 (SEM) mm Hg, P less than 0-01. When the rectum was distended by a balloon inflated with 100 ml of air a fall in anal sphincter pressure to 33+...

Nitrate contamination in ground and surface water is an increasingly serious environmental problem and only a few bacterial strains have been identified that have the ability to remove nitrogen pollutants from wastewater under thermophilic conditions. We therefore isolated thermophilic facultative bacterial strains from wood chips that had been composted with swine manure under aerated high tem...

OBJECTIVE To determine whether, in the era of sentinel lymph node (SLN) biopsy, head and neck melanoma (HNM) has a poorer outcome than melanomas at other sites (OMS). DESIGN Prospective database, 1994 to 2004. Characteristics and outcomes of patients with HNM vs those with OMS were analyzed by Fisher test, paired t test, and chi(2) test. SETTING Tertiary referral center. PATIENTS A total ...

To evaluate the reactivity to psychological stress in patients with essential hypertension we investigated hemodynamic and endocrinologic changes during a mental arithmetic task (MAT) and a mirror drawing test (MDT) in 10 hypertensive subjects. Hemodynamic changes were assessed continuously using an ambulatory radionuclide cardiac detector. There were significant increases in systolic blood pre...

The objective of the present real-time in vivo experiment was to assess guided bone regeneration (GBR) in standardized calvarial defects using particulate graft material (Bio-Oss) and β-tricalcium phosphate (β-TCP) with adjunct recombinant human platelet-derived growth factor (rhPDGF) therapy. Eighteen female Sprague-Dawley rats with a mean age and weight of 8 ± 0.53 weeks and 250 ± 0.49 g, res...

Background: Despite recent technical improvement in assisted reproductive techniques (ART), the implantation rate per embryo still remains low (15%). The aim of the study is to determine whether the failure of IVF cycle is associated with endometrial thickness on the day of HCG (human chorionic gonadotropin) administration. Materials and Methods: Endometrial thickness of two hundred and seven p...

A thermophilic bacterium that can use O2, NO3-, Fe(III), and S0 as terminal electron acceptors for growth was isolated from groundwater sampled at a 3.2-km depth in a South African gold mine. This organism, designated SA-01, clustered most closely with members of the genus Thermus, as determined by 16S rRNA gene (rDNA) sequence analysis. The 16S rDNA sequence of SA-01 was >98% similar to that o...

Basal heart rate (HR) of conscious rats under resting conditions was measured daily by electrocardiogram (ECG) during the development of one-kidney, one clip (1K1C) hypertension. A progressive increase in HR (mean +/- SEM) was observed from Day 1 to 7: 318 +/- 11; 330 +/- 18, 338 +/- 18; 344 +/- 19; 372 +/- 14; 374 +/- 11, and 388 +/- 12 bpm, respectively. During the same period, mean arterial ...