1. The pain level of patients in the different publications is not mentioned. We know from clinical trial experience with tapentadol that patients had moderate to severe pain (most even severe pain). The pain level of patients in studies with duloxetine, naproxen and celecoxib might have been lower; at least we would extrapolate this from the dosages used. Based on this, we doubt if the compara...

Underthrusting and the elastic-rebound theory are consistent with the gross static deformations after earthquakes for island-arc regions such as Japan, Alaska, and Chile. Yet anomalous, time-dependent post-earthquake adjustments suggest additional processes. Here the asthenosphere or mantle becomes the element that both determines the post-seismic deformation and controls the accumulation of st...

Background: It is expected that about 65,000 new patients will be diagnosed with head and neck cancer in 2017 in the United States. Patients with recurrent or advanced or metastatic head and neck do not have good survival due to aggressive and recurrent nature of this cancer. Moreover, cumulative and residual toxicities from previous and ongoing treatments significantly impede quality of remain...

Purpose: Analysis of the efficacy of fast neutron radiotherapy in the treatment of adenoid cystic carcinomas (ACC) of the salivary glands, identification of prognostic variables and dedifferentiation after radiotherapy. Patients and Methods: Histological slides of primary and recurrent lesions of 71 patients were reviewed to confirm the diagnosis and to analyse subtypes. Median follow-up was 52...

BACKGROUND The emergence of human malaria due to the monkey parasite Plasmodium knowlesi threatens elimination efforts in southeast Asia. Changes in land use are thought to be driving the rise in reported P knowlesi cases, but the role of individual-level factors is unclear. To address this knowledge gap we assessed human and environmental factors associated with zoonotic knowlesi malaria risk....

Features of consciousness difficult to understand in terms of conventional neuroscience have evoked application of quantum theory, which describes the fundamental behavior of matter and energy. In this paper we propose that aspects of quantum theory (e.g. quantum coherence) and of a newly proposed physical phenomenon of quantum wave function "self-collapse" (objective reduction: OR Penrose, 199...

Keywords--Model-based, Neural networks, Spectrum estimation, Entropy, Ionosphere, Radar, Propagation, Clutter. 1. I N T R O D U C T I O N Model-based neural networks utilize internal models of signals, processes, or objects in order to combine adaptive learning with a priori knowledge. One of the first model-based neural network was Widrow's Adaline (Widrow, 1959). Several neural networks based...

0049: LOCAL ANAESTHETIC TOXICITY: FOCUSED TEACHING IMPROVES SURGEONS’ KNOWLEDGE Usman Khalid , Aeliya Zaidi , Michael Lamyman , Marc Swan . 1 Stoke Mandeville Hospital, Aylesbury, UK; Morriston Hospital, Swansea, UK. Aim: Local anaesthetic (LA) is routinely used by Plastic Surgeons. Toxicity can lead to potentially fatal complications. The aim of this audit was to determine the current awarenes...

BACKGROUND Laser ablation under an epiduroscopic view allows for the vaporization of a small amount of the nucleus pulposus, causing a reduction in intradiscal pressure and relief of radicular pain. Currently, Ho:YAG and Nd:YAG lasers are commonly used for spinal diseases. However, the use of the Nd:YAG laser for intra-spinal procedures can be limited because of thermal injury and low efficacy....

Components of the glycocalyx are being intensively studied for their involvement in a vast array of glomerular diseases. Among the most abundant proteoglycans in the glomerular cell glycocalyx are the heparan sulfate proteoglycans Glypican-1 and 5, expressed predominantly in glomerular endothelial and epithelial cells, respectively. We used a previously characterized zebrafish model to define t...