نتایج جستجو برای: گیرنده a1 آدنوزینی
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Let φ(x1, . . . , xh, y) = u1x1 + · · · + uhxh + vy be a linear form with nonzero integer coefficients u1, . . . , uh, v. Let A = (A1, . . . , Ah) be an h-tuple of finite sets of integers and let B be an infinite set of integers. Define the representation function associated to the form φ and the sets A and B as follows: R (φ) A,B (n) = card ({(a1, . . . , ah, b) ∈ A1 × · · · × Ah × B : φ(a1, ....
SP-A (surfactant protein A) is a membrane-associated SP that helps to maintain the lung in a sterile and non-inflamed state. Unlike SP-As from other mammalian species, human SP-A consists of two functional gene products: SP-A1 and SP-A2. In all the functions examined, recombinant human SP-A1 invariably exhibits lower biological activity than SP-A2. The objective of the present study was to inve...
Most individuals carry two wild-type M alleles of the SERPINA1 gene which encodes a1-antitrypsin. 95% of severe deficiency of a1-antitrypsin is associated with the Z allele (Glu342Lys; denoted PiZZ in the homozygote), and with the retention and polymerisation of a1-antitrypsin within hepatocytes [1]. These polymers are contained within periodic acid–Schiff-positive, diastase-resistant inclusion...
........................................................................................................77 Populärvetenskaplig Sammanfattning...........................................................78 References.....................................................................................................79
SGR 1900+14 had a brief episode of exceedingly rapid spindown immediately following its 1998 Aug. 27 superburst. On a timescale of hours, it increased its period by a part in 10. The corresponding Ṗ ∼ 10 is orders of magnitude higher than the typical quiescent rate of Ṗ ∼ 6×10.
We assume two loci under selection (A and B) and a third neutral locus C, each with two alleles denoted by A1 and A2, B1 and B2, and C1 and C2, respectively. Let the frequencies of alleles A1, A2, B1, B2, C1 and C3 be p, 1 p, q, 1 q, n and 1 n, respectively. We denote the recombination rate between locus i and j by rij and consider a continuous-time model, such that second-order terms of recomb...
Besides its nutritional value, bovine beta-casein is a source of bioactive peptides called betacasomorphins produced during digestion of raw or processed milk. It was shown that the betacasomorphin 7 originates only from beta-casein variants A1 or B and may be a significant risk factor in human ischemic heart disease, arteriosclerosis, type I diabetes and sudden infant death syndrome. In this s...
Hyperoxic acute lung injury (HALI) is characterized by a cell death response with features of apoptosis and necrosis that is inhibited by IL-11 and other interventions. We hypothesized that Bfl-1/A1, an antiapoptotic Bcl-2 protein, is a critical regulator of HALI and a mediator of IL-11-induced cytoprotection. To test this, we characterized the expression of A1 and the oxygen susceptibility of ...
We have investigated the molecular mechanisms underlying the ability of peripheral blood monocytes to block apoptosis induction in endothelial cells. Monocytes stimulated the expression of the bcl-2 homologue A1 in serum-starved endothelial cells after 6 h of coincubation, with elevated A1 levels persisting for up to 21 h. IL-1 and TNF also stimulated A1 expression at 6 h, but A1 transcript lev...
Bacillus circulans WL-12, isolated as a yeast cell wall-lytic bacterium, secretes a variety of polysaccharide-degrading enzymes into culture medium. When chitinases of the bacterium were induced with chitin, six distinct chitinase molecules were detected in the culture supernatant. These chitinases (A1, A2, B1, B2, C, and D) showed the following distinct sizes and isoelectric points: Mr 74,000,...
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