Extracts from Hypericum perforatum (St. John’s wort; Clusiaceae) are widely used for the treatment of mild to moderate depression. Four classes of constituents – hyperforins, hypericins, flavonoids, and xanthones – appear to contribute to the antidepressant activity. Interestingly, all four classes of secondary metabolites involve polyketide derivatives. Key reactions of their biosyntheses are ...

OBJECTIVE In this study, we aimed at evaluation of the efficacy of Hypericum perforatum and flaxseed on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women. MATERIALS AND METHODS We searched MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials (RCT) to explore trials that assessed the effectiveness of H. perforatum and flaxseed on hot flash, vagina...

Plant extract is a complex concoction of several phytochemicals, for instance, phenolics, sugars, flavonoids, xanthones, and others. In general, it said that hydroxyl-rich phenolics act as reducing agents metal ions, but little discussed about the stabilizing ligands nanoparticles (NPs). Thus, despite popularity plant extract-mediated synthesis NPs, phytochemical basis process exact mechanism a...