Over the last decade, telomere length (TL) has gained attention as a potential biomarker in cancer disease. We previously reported that long blood TL was associated with a poorer outcome in patients with breast cancer and renal cell carcinoma. Based on these findings, we hypothesized that certain immunological components may have an impact on TL dynamics in cancer patients. One aim of the prese...

Cluster-cluster transitions in the periodically illuminated photosensitive Belousov-Zhabotinsky (BZ) reaction-diffusion system exhibit the same scenario as in the autonomous BZ system with negative global feedback: two-phase clusters <--> three-phase clusters <--> irregular clusters <--> localized clusters. Transitions induced by changing the dark ( TD) or light ( TL) phases of the periodic ext...

Thallium is one of the most toxic elements, without known biological function in living beings. While contents of other heavy metals like Cd, Hg and Pb are subject to strict limitations in foodstuffs and medicinal plants, and concentrations are routinely checked, in the case of Tl there are no regulations in prime matters intended for phytomedicines, and its monitorization is not performed. The...

We have investigated the number of structural genes present in ASL-1 cells, a murine leukemia cell line which encodes the heavy chain of thymus leukemia (TL) antigens, a protein which is similar to the Class I histocompatibility antigens. TL-specific messenger RNA was purified from polysomes of ASL-1 cells by immunoprecipitation, and this messenger RNA translated in vitro to produce a Mr 42,000...

Transfer Learning (TL) is the branch of Machine Learning concerned with improving performance on a target task by leveraging knowledge from a related (and usually already learned) source task. TL is potentially applicable to any learning task, but in this survey we consider TL in a Reinforcement Learning (RL) context. TL is inspired by psychology; humans constantly apply previous knowledge to n...

The aim of this study was to investigate the effects of training programs on serum lipid profile and myocardial oxidative stress. Male Wistar rats (2 mo-old) were divided into three groups (n = 8): sedentary (S), loadless trained (T) and trained-overload 2% body weight (TL). T and TL were trained through swimming for 9 weeks. T and TL rats had increased myocardial lipoperoxide (TBA) and lipid h...

Thallium-201/Nasal administration/Biological safety/Preclinical study. Nasal administration of thallium-201 (Tl) has previously been shown to be useful for the assessment of olfactory nerve connectivity in vivo. We assessed the biological effects of nasal Tl administration in mice to determine its safety before conducting clinical trials on humans. Tl uptake was evaluated in normal mice (n = 5)...

This report describes the sex differentiation of the Korean rose bitterling, Rhodeus uyekii, from hatching to 170 days post-hatch (DPH) in relation to total length (TL), body weight (BW), and integral water temperature (IWT). The growth curve of TL from just hatching to 83 DPH was 5.144e0.045t (R² = 0.961; t, time), and that of BW was 2.398e0.086t (R² = 0.725). Primordial germ cells (PGCs) were...

The interesting article by CHINN et al. [1] explored the relationship of transfer factor (TL) or diffusing capacity to alveolar volume (VA) within normal subjects at different depths of inspiration and between normal subjects having lungs of different sizes, and found that the ratio TL/VA (often called the carbon monoxide transfer coefficient (KCO)) varied with VA itself (i.e. lung size) as wel...

BACKGROUND leukocyte telomere length (TL) is considered a marker of biological aging. Several studies have investigated the link between leukocyte TL and aging-associated functional attributes of the brain, but no prior study has investigated whether TL can be linked to brain atrophy and white matter hyperintensities (WMHs); two prominent structural manifestations of brain aging. METHODS we i...