نتایج جستجو برای: ژن myh7

تعداد نتایج: 16107  

Journal: :Genes 2023

microRNAs are a class of small RNAs that have been extensively studied, which involved in many biological processes and disease occurrence. The incidence intrauterine growth restriction is higher mammals, especially multiparous mammals. In this study, we found the weight longissimus dorsi growth-restricted pigs was significantly lower than normal pigs. Then, pig were used to characterize miRNA ...

2017
Julianny Freitas Rafael Fernando Eugênio dos Santos Cruz Filho Antônio Carlos Campos de Carvalho Ilan Gottlieb José Guilherme Cazelli Ana Paula Siciliano Glauber Monteiro Dias

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant genetic disease caused by mutations in genes encoding sarcomere proteins. It is the major cause of sudden cardiac death in young high-level athletes. Studies have demonstrated a poorer prognosis when associated with specific mutations. The association between HCM genotype and phenotype has been the subject of several studies since the d...

Journal: :Biophysical Journal 2021

Myosin is an essential driver of cardiac and skeletal muscle function. Multiple mutations identified in β-cardiac/skeletal slow myosin heavy chain (MYH7) fast 2A (MYH2), cause a group human diseases termed myosinopathies1. Over 90% these are found the filament-forming region coiled-coil tail, also known as light meromyosin (LMM). A mutation to proline residue or deletion single-residue common m...

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