BACKGROUND Tracheobronchial mucoepidermoid carcinoma (MEC) is a rare airway tumor in adults for which surgery is considered a first-line treatment. However, some patients already lost the best opportunity of a surgical intervention when diagnoses are confirmed, and surgery causes considerable trauma resulting in partial loss of pulmonary function. Moreover, the tumor is resistant to radiotherap...

BACKGROUND Methicillin-resistant coagulase-negative staphylococci (MR-CoNS) are opportunistic pathogens and serve as a large reservoir of staphylococcal cassette chromosome mec (SCCmec). Characterization of SCCmec in MR-CoNS can generate useful information on the mobilization and evolution of this element. METHODOLOGY/PRINCIPAL FINDINGS Non-repetitive MR-CoNS clinical isolates (n = 84; 39 S. ...

Mucoepidermoid carcinoma (MEC), one of the most common salivary gland malignancies, is rare in children. MEC mainly occurs in the parotid gland, along with minor glands being the second common site, particularly in palate. Clinical, histological, and radiological findings of palatal MEC in a 12-year-old girl are presented with three-year follow-up. Pathologic lesions must be considered in diffe...

The Minimum Error Correction (MEC) approach is used as a metric for reconstruction of haplotypes from NGS reads. In this paper, we show that the MEC may encounter with imprecise reconstructed haplotypes for some NGS devices. Specifically, using mathematical derivations, we evaluate this approach for the SOLiD, Illumina, 454, Ion, Pacific BioSciences, Oxford Nanopore, and 10X Genomics devices. O...

Mucoepidermoid cancer (MEC) of the bronchus is composed of an admixture of mucus secreting, intermediate and squamous cell types. 2 Although the clinical features of the bronchial MEC are identical to those in adults, such as recurrent pneumonia, cough and/or hemoptysis, the diagnosis is often unsuspected in children because of the rarity of the condition. Here, we report a 13-year-old boy with...

SUMMARY BACKGROUND Mucoepidermoid carcinoma (MEC), which is primarily found in the salivary glands, is rarely seen in the breast. These tumors usually develop from squamous and mucus-secreting cells. Histological grading is an important prognostic factor. CASE REPORT We present herein a case of a 69-year-old female patient with a painful mass in the left breast. Of importance is that, in a...

It is not understood why, after onset of left bundle-branch block (LBBB), acute worsening of cardiac function is followed by a further gradual deterioration of function, whereas most adverse cardiac events lead to compensatory adaptations. We investigated whether mechano-electrical coupling (MEC) can explain long-term remodeling with LBBB and cardiac resynchronization therapy (CRT). To this pur...

Full characterization of methicillin-resistant Staphylococcus aureus (MRSA) requires definition of not only the bacterial genetic background but also the structure of the complex and heterologous mec element these bacteria carry, which is associated with drug resistance determinant mecA. We report the development, validation, and application of a multiplex PCR strategy that allows quick presump...