به طور کلی، هر سلول طبیعی بدن انسان، که مشتمل بر قسمت‌های مختلفی همچون هسته، غشاء سلولی و نانوالیاف پروتئینی می‌باشد، دارای سختی استحکام مکانیکی مشخصی است. هرگونه تغییر محسوس در این استحکام، نشان از یک بیماری دارد. یکی راه‌های تشخیص بیماری‌های مختلف سرطان های سنجش میزان تغییرات رخ داده خواص آن‌ها می‌باشد. مقالۀ حاضر، مشخصات شامل مدول الاستیسیته نیروی چسبندگی Ago-1522 سلول‌های پوست محسوب می‌شود،...

objective(s):despite of wide range applications of polymeric nanoparticles in protein delivery, there are some problems for the field of protein entrapment, initial burst and controlled release profile.   materials and methods: in this study, we investigated the influence of some changes in plga nanoparticles formulation to improve the initial and controlled release profile. selected parameters ...

introduction: a close link between spreading depression (sd) and several neurological diseases such as epilepsy could be demonstrated in many experimental studies. epilepsy is among the most common brain disorders. despite a large number of investigations, its mechanisms have not been yet well elucidated. hippocampus is one of the important structures involved in seizures. the aim of this study...

Burst firing of dopaminergic neurons in ventral tegmental area (VTA) induces a large transient increase in synaptic dopamine (DA) release and thus is considered the reward-related signal. But the mechanisms of burst generation of dopaminergic neuron still remain unclear. This experiment investigated the burst firing of VTA dopaminergic neurons in rat midbrain slices perfused with carbachol and ...

With the increasing interest in optical burst switching (OBS) networks, the performance assessment of this kind of networks became of particular concern. Recently, some authors suggested that burst loss was not a reliable performance assessment metric for OBS networks. Refuting this claim, this paper presents simulation results obtained for a ring network, using real tributary IPv4 packets as s...

A time-scale invariant burst-detection algorithm for single-unit spike train is described. This burst analysis is an auto-adaptive algorithm that uses interand intra-burst intervals for identifying the burst itself. By using a self-adaptive algorithm, a burst is de$ned by the characteristic $ring patterns within and between bursts. Bursts are detected by auto-adaptive method when the inter-burs...

Optical burst switching (OBS) is one of the most promising nextgeneration all-optical data transport paradigms. As networks become increasingly distributed and autonomic, Optical Burst Switching becomes the right choice for the next generation optical Internet. In this paper, we propose a mechanism for Dynamic Routing of Reliability-Differentiated connections (DRRDC) in Optical Burst Switched n...

This paper analyzes the effects of a convulsant and an anticonvulsant manipulation on spontaneous bursts in CA3 pyramidal cells in the in vitro slice preparation under conditions of low (3.3 mM [K(+)](o)) and high (8.5 mM [K(+)](o)) burst probability. When burst probability was low, the anticonvulsant, pentobarbital, produced the anticipated effects: the burst duration decreased and interburst ...

In this paper, the optical composite burst switching (OCBS) technique is proposed to be implemented in an all-optical backbone network to support Internet protocol (IP) traffic. The OCBS is based on two main features. First, several IP packets are assembled in a single macropacket, called burst. Second, the burst contention in an optical switch is handled by means of two techniques, the wavelen...

Pyramidal cells in the electrosensory lateral line lobe (ELL) of weakly electric fish have been observedto produce high-frequency burst discharge with constant depolarizing current (Turner et al., 1994). We present a two-compartment model of an ELL pyramidal cell that produces burst discharges similar to those seen in experiments.The burst mechanism involves a slowly changing intera...