Bone morphogenetic protein (BMP)-2 induces bone and cartilage tissue formation. Large amounts of BMP-2 are difficult to purify or to produce in vitro using eukaryotic cells. The goal of the present study was to assess the clinical use of Escherichia coli-derived recombinant human BMP-2 (ErhBMP-2) on bone fusion after cervical and lumbar spine surgery in a goat model, compared with the standard ...

The uterine cervix is a rare implantation site for ectopic pregnancy, surgical management should be carefully considered due to the risk of severe hemorrhage associated with this treatment. Methotrexate (MTX) is well documented as an effective medical approach in early gestations and low human chorionic gonadotropin (ß-hCG) levels yielding good results. This is the case,of a 39 year old woman w...

Although recreational dancing is associated with increased physical and psychological well-being, little is known about the harmful effects of excessive dancing. The aim of the present study was to explore the psychopathological factors associated with dance addiction. The sample comprised 447 salsa and ballroom dancers (68% female, mean age: 32.8 years) who danced recreationally at least once ...

The derivatives of hydroxybenzoic and hy­ droxycinnamic acids are widespread in the plant kingdom. A considerable number of these deriva­ tives are well known [1], Nevertheless there is only little existing information about the glucosides of these compounds and their distribution. Syringic acid-O-ß-D-glucoside was detected in Anodendron affine. [2], as well as /»-hydroxybenzoic acid-O-ß-D-gluc...

Two new triterpenoid saponins have been isolated from leaves and flowers of Crotalaria madurensis Wight&Arn named; sophradiol 3-O-β-D-C1-glucopyranosyl-(1''→4')-O-β-DC1 glucuronopyranoside (3) and sophradiol 3-Oα-LC4rhamnopyranosyl (1'''→4'')-O-ß-D-C1 glucopranosyl-(1''→6')-O-ß-DC1-glucopyranoside (4) beside myo-inositol (1) and three other triterpene saponin their structures were established a...

The aim of this study was to investigate the pathogenic potential and antibiotic resistance 59 Escherichia coli isolates from ready-to-eat (RTE) street food (n = 31) drinking water 28) sold in city Maputo, Mozambique. were characterized by XbaI subtyping analysis via pulsed field gel electrophoresis. Multiplex PCRs performed targeting five virulence genes (stx, lt, st, astA, eae) three groups a...

Chronic exposure (24-72 hrs) of pancreatic islets to elevated glucose and fatty acid leads to glucolipoxicity characterized by basal insulin hypersecretion and impaired glucose-stimulated insulin secretion (GSIS). Our aim was to determine the mechanism for basal hypersecretion of insulin. We used mono-oleoyl-glycerol (MOG) as a tool to rapidly increase lipids in isolated rat pancreatic ß-cells ...

G protein-coupled receptors (GPCRs) mediate a wide variety of physiological function. GPCR signaling is negatively regulated by the receptor desensitization, a procedure initiated by a group of kinases, including GPCR kinases (GRKs). Studies using gene-targeted mice revealed that deficiency of a particular GRK member led to dysfunction of a highly selective group of GPCRs. In particular, for ex...

PURPOSE The purpose of this article is to educate nurse practitioners about the pathophysiology surrounding the development of portal hypertension and the effective use of nonselective ß-blockers to prevent primary bleeding and decrease the mortality risk. DATA SOURCES The articles included were retrieved via ISI Web of Science using the years 2004-2009 and key words cirrhosis, portal hyperte...