نتایج جستجو برای: هپاتوسلولار کارسینوما hcc

تعداد نتایج: 14492  

Farzan Modaresi, Fraidoon Kavoosi, Masumeh Sanaei,

The basic unit of chromatin is a nucleosome included an octamer of the four core histones and 147 base pairs of DNA. Posttranslational histones modifications affect chromatin structure resulting in gene expression changes. CpG islands hypermethylation within the gene promoter regions and the deacetylation of histone proteins are the most common epigenetic modifications. The aberrant patterns of...

Journal: :Hepatology 2012
Sufen Shang Amelie Plymoth Shaokui Ge Ziding Feng Hugo R Rosen Suleeporn Sangrajrang Pierre Hainaut Jorge A Marrero Laura Beretta

UNLABELLED The aim of this study was to identify a biomarker that could improve alpha-fetoprotein (AFP) performance in hepatocellular carcinoma (HCC) surveillance among patients with cirrhosis. We performed proteomic profiling of plasma from patients with cirrhosis or HCC and validated selected candidate HCC biomarkers in two geographically distinct cohorts to include HCC of different etiologie...

2016
Zhonghu Li Xin Zhao Peng Jiang Senlin Xiao Guo Wu Kai Chen Xi Zhang Hui Liu Xiuguo Han Shuguang Wang Xiaowu Li

Controversy exists regarding pathological factors affecting the prognosis of hepatocellular carcinoma (HCC) patients with hepatitis B virus (HBV-HCC). Their postoperative clinical behaviors and the exact HBV Deoxyribonucleic Acid (DNA) thresholds that distinguish good and poor prognoses are unknown. This study aimed to compare clinicopathological, pre- and postoperative clinical factors and ove...

Journal: :Nanoscale advances 2023

Microwave ablation (MWA) is a promising minimally invasive therapy for hepatocellular carcinoma (HCC). However, the efficiency of MWA in treating HCC evidently limited by incomplete large...

Journal: :Annals of surgery 2015
Tohru Utsunomiya Mitsuo Shimada Masatoshi Kudo Takafumi Ichida Osamu Matsui Namiki Izumi Yutaka Matsuyama Michiie Sakamoto Osamu Nakashima Yonson Ku Tadatoshi Takayama Norihiro Kokudo

OBJECTIVE To compare the prognostic factors and outcomes after hepatic resection among patients with hepatitis B virus (HBV)-positive, hepatitis C virus (HCV)-positive, and negative for hepatitis B surface antigen and hepatitis C antibody, so-called "NBNC"-hepatocellular carcinoma (HCC) using the data from a nationwide survey. BACKGROUND The incidence of NBNC-HCC is rapidly increasing in Japa...

2013
Aileen Marshall Margus Lukk Claudia Kutter Susan Davies Graeme Alexander Duncan T. Odom

BACKGROUND Liver cirrhosis is the most important risk factor for hepatocellular carcinoma (HCC) but the role of liver disease aetiology in cancer development remains under-explored. We investigated global gene expression profiles from HCC arising in different liver diseases to test whether HCC development is driven by expression of common or different genes, which could provide new diagnostic m...

Journal: :Hepatology 2003
Makoto Chuma Michiie Sakamoto Ken Yamazaki Tsutomu Ohta Misao Ohki Masahiro Asaka Setsuo Hirohashi

Hepatocellular carcinoma (HCC) associated with chronic liver disease evolves from precancerous lesions and early HCC to a progressed form. Nodule-in-nodule-type HCC (progressed HCC within early HCC) represents the transition from early to progressed HCC and, therefore, is useful in molecular genetic analysis of HCC progression during multistage carcinogenesis. We compared expression profiles am...

Journal: :Nature Reviews Gastroenterology & Hepatology 2018

ژورنال: :hormozgan medical journal 0
مریم توحیدی m tohidi گروه پاتولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی هرمزگان، بندرعباس، ایران سیدعبداله موسوی s.a moosavi فرزاد حدایق f hadaegh

مقدمه: کارسینوم فولیکولار تیروئید، دومین بدخیمی شایع تیروئید بوده و بیشتردر زنان و با حداکثر شیوع در دهه های پنجم و ششم زندگی دیده می شود. این تومور در صورت تهاجم به عروق خونی، می تواند متاستاز دور دست به استخوان، ریه، کبد و سایر اعضا بدهد. کارسینوم فولیکولار تیروئید، بندرت بصورت متاساز دوردست و به خصوص به شکل متاساز منفرد تظاهر می یابد. معرفی بیمار: مورد معرفی شده، خانم 65 ساله ای می باشد که ب...

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