شرایط اکولوژیک مثل دسترسی به غذای کافی و مناسب از عواملی است که می‌تواند روی رفتار جانوران تاثیرگذار باشد. حشرات مختلفی در زمان گرسنگی سعی می‌کنند تا رفتارهای آمیزشی طول مدت آمیزش را کاهش دهند. هدف این مطالعه، بررسی اثر بر عملکرد کفشدوزک Hippodamia variegata بود. آزمایش، نرها ماده‌های ۱۰ ۱۵ روزه باکره استفاده شد. هر تکرار، یک نر ماده ۳ ساعت (از ۱۲ الی ۱۵) برای کنار هم قرار داده شدند ‌زمان تاخیر...

Correlations between neural activity in primary motor cortex (M1) and arm kinematics have recently been shown to be temporally extensive and spatially complex. These results provide a sophisticated account of M1 processing and suggest that M1 neurons encode high-level movement trajectories, termed "pathlets." However, interpreting pathlets is difficult because the mapping between M1 activity an...

Delamanid, a new anti-tuberculosis drug, is metabolized to M1, a unique metabolite formed by cleavage of the 6-nitro-2,3dihydroimidazo[2,1-b] oxazole moiety, in plasma albumin in vitro. The metabolic activities in dogs and humans are higher than those in rodents. In this study, we characterized the pharmacokinetics and metabolism of delamanid in animals and humans. Eight metabolites (M1–M8) pro...

OBJECTIVE To investigate the effects of simultaneous, bihemispheric, dual-mode stimulation using repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) on motor functions and cortical excitability in healthy individuals. METHODS Twenty-five healthy, right-handed volunteers (10 men, 15 women; mean age, 25.5 years) were enrolled. All participants ...

OBJECTIVE To characterize the phenotypic changes of adipose tissue macrophages (ATMs) under different conditions of insulin sensitivity. RESEARCH DESIGN AND METHODS The number and the expressions of marker genes for M1 and M2 macrophages from mouse epididymal fat tissue were analyzed using flow cytometry after the mice had been subjected to a high-fat diet (HFD) and pioglitazone treatment. ...

BACKGROUND AND PURPOSE Repetitive transcranial magnetic stimulation of the primary motor cortex (M1) may improve outcomes after stroke. The aim of this study was to determine the effects of M1 theta burst stimulation (TBS) and standardized motor training on upper-limb function of patients with chronic stroke. METHODS Ten patients with chronic subcortical stroke and upper-limb impairment were ...

21 The role of primary motor cortex (M1) in the control of voluntary movements is still 22 unclear. In brain functional imaging studies of unilateral hand performance, bilateral M1 23 activation is inconsistently observed and disruptions of M1 using repetitive transcranial 24 magnetic stimulation (rTMS) lead to variable results in the hand motor performance. As 25 the motor tasks differed quali...

In primates, the refinement of motor behaviors, in particular hand use, is associated with the establishment of more direct projections from primary motor cortex (M1) onto cervical motoneurons [1, 2] and the appearance of additional premotor and sensory cortical areas [3]. All of these areas have reciprocal connections with M1 [4-7]. Thus, during the evolution of the sensorimotor network, the n...