Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses. IL-18 is expressed at sites of chronic inflammation, in autoimmune diseases, in a variety of cancers, and in the context of numerous infectious diseases. This short review will describe the basic biology of IL-18 and thereafte...

In previous chapters we have set down, with some discrimination, the contributions to the record of structural aspects of morphogenesis in the watermolds. Only in passing have we touched upon the factors that trigger or modify the genetically dictated form these fungi may take. This and the following three chapters review the literature dealing with external and internal factors that influence ...

What are community networks? I am writing as a librarian and network user who has been involved in using telecommunications to communicate with other people and to provide information on a wide range of subjects. I have encouraged people in various towns and counties to use this technology to start and use networks that can strengthen the community. Many individuals, organizations, and institut...

Never in history has democracy been more pervasive throughout the world. Yet, available evidence points to a growing, widespread crisis of legitimacy of governments, parliaments, political parties, and politicians in most countries, including the United States and Western Europe. 1 Because the Internet is seen as the ultimate technology of freedom, its diffusion among citizens has been hailed a...