The fusion peptide (FP) in the N terminus of the HIV envelope glycoprotein, gp41, functions together with other gp41 domains to fuse the virion with the host cell membrane. We now report that FP colocalizes with CD4 and TCR molecules, coprecipitates with the TCR, and inhibits antigen-specific T cell proliferation and proinflammatory cytokine secretion in vitro. These effects are specific: T cel...

Fluorescent proteins (FPs) emerged in the mid 1990s as a powerful tool for life science research. Cyan FPs (CFPs), widely used in multicolor imaging or as a fluorescence resonance energy transfer (FRET) donor to yellow FPs (YFPs), were considerably less optimal than other FPs because of some relatively poor photophysical properties. We recently initiated an effort to create improved or alternat...

Functional pain syndromes (FPS) characterize a subset of individuals who experience pain and related symptoms and disability without clear structural or disease etiology. In the pediatric population, FPS hold high clinical importance due to significant prevalence rates and potential to persist into adulthood. Although extensive research has been executed to disambiguate FPS, the syndromes that ...

Nowadays, automatic speech recognizers have become quite good in recognizing well prepared fluent speech (e.g. news readings). However, the recognition of spontaneous speech is still problematic. Some reasons for this are that spontaneous speech is usually less articulated and that it can contain a lot of disfluencies such as filled pauses (FPs), abbreviatons, repetitions, etc. In this paper, a...

Most algorithms for mining frequent patterns in data streams are based on structures like FP-tree, complex mining method makes time and storage space large compared to the bit vector expression. In this paper, an algorithm based on Horizontal Bit vectors for mining Frequent Patterns in data Streams HB-FPS is proposed. HB-FPS is divided into two phases, in online phase, it uses bit vectors to ho...

A new method of farthest point strategy (FPS) for progressive image acquisition-an acquisition process that enables an approximation of the whole image at each sampling stage-is presented. Its main advantage is in retaining its uniformity with the increased density, providing efficient means for sparse image sampling and display. In contrast to previously presented stochastic approaches, the FP...

One of the major challenges in computer-aided detection (CAD) of polyps in CT colonography (CTC) is the reduction of false-positive detections (FPs) without a concomitant reduction in sensitivity. A large number of FPs is likely to confound the radiologist's task of image interpretation, lower the radiologist's efficiency, and cause radiologists to lose their confidence in CAD as a useful tool....

Almost 65% of the Tanzanian population is under the age of 24 and almost 20 % of the population is aged 15-24 years. Yet, this important group faces many significant health challenges, such as early sexual debut, early pregnancies, risky behaviours and sexually transmitted infections. The objective of this study was to assess knowledge, attitudes and practices on family planning services among ...

Off-line scheduling and fixed priority scheduling (FPS) are often considered as complementing and incompatible paradigms. A number of industrial applications demand temporal properties (predictability, jitter constraints, end-to-end deadlines, etc.) that are typically achieved by using off-line scheduling. The rigid off-line scheduling schemes used, however, do not provide for flexibility. On t...