Pulmonary embolism (PE) remains one of the leading causes of cardiovascular morbidity and mortality [1]. Acute PE has a spectrum of clinical syndromes and varying clinical outcomes [2, 3]. Estimation of patient prognosis helps to prioritise appropriate management strategies. Risk stratification of patients with PE may identify patients at high risk of early PE-related death who may benefit from...

We have demonstrated that in rats activities of various enzymes related to gluconeogenesis and amino acid metabolism show circadian rhythms. Based on these results, we have explored the molecular mechanisms underlying circadian oscillation and phase response to light of the master clock located in the dorsomedial subdivision of the suprachiasmatic nucleus (SCN) and found various proteins closel...

Relatively little is known about the genetic control of agronomic traits in common wheat (Triticum aestivum L.) compared with traits that follow Mendelian segregation patterns. A doubled-haploid population was generated from the cross RL4452x'AC Domain' to study the inheritance of the agronomic traits: plant height, time to maturity, lodging, grain yield, test weight, and 1000-grain weight. Thi...

با توجه به رشد بالای جمعیت در جهان و نیاز اطمینان از امنیت غذایی، افزایش تولید واحد سطح محصولات زراعی به‌منزلة راهبردی اساسی حل مسئلة تأمین غذا به‌شمار می‌رود. سوی دیگر، وجود محدودیت زیرکشت پایین‌بودن میانگین عملکرد برخی کشاورزی مانند گندم کشور، محصول می‌تواند راهکاری عملی پاسخ کشور محسوب شود. یکی مهم‌ترین بیماری‌های فوزاریوم است که، نقش پیش‌بینی این بیماری جلوگیری کاهش بهره‌وری محصول، مدل‌هایی...

The retinohypothalamic tract (RHT) is a retinofugal neuronal pathway which, in mammals, mediates nonimage-forming vision to various areas in the brain involved in circadian timing, masking behavior, and regulation of the pupillary light reflex. The RHT costores the two neurotransmitters glutamate and pituitary adenylate cyclase activating peptide (PACAP), which in a rather complex interplay are...

The most common dwarfing genes in wheat, Rht-B1b and Rht-D1b, classified as gibberellin-insensitive (GAI) dwarfing genes due to their reduced response to exogenous GA, have been verified as encoding negative regulators of gibberellin signaling. In contrast, the response of gibberellin-responsive (GAR) dwarfing genes, such as Rht12, to exogenous GA is still unclear and the role of them, if any, ...

Greater early vigour has potential for increasing biomass and grain yields of wheat crops in Mediterranean-type environments. Embryo size is an important determinant of early vigour in barley and likely to contribute to greater vigour in wheat. Little is known of the underlying genetic control for embryo size, or its genetic association with early vigour in wheat. Over 150 doubled-haploid lines...