Cell permeabilization by electric pulses (EP), or electroporation, is widely used for intracellular delivery of drugs and plasmids, as well as for tumour and tissue ablation. We found that cells pre-treated with 100-μs EP develop delayed hypersensitivity to subsequent EP applications. Sensitizing B16 and CHO cells by splitting a single train of eight 100-μs EP into two trains of four EP each (w...

To gain insight into the mammalian liver to kidney erythropoietin (Ep) switch, we heterotopically transplanted livers from preswitch, switched, and postswitch fetal and newborn lambs into normal adult sheep. Recipients' serum Ep and circulating reticulocyte levels were serially determined until rejection of the graft and compared with identical samples from sham-operated control adult ewes. Tra...

Erythropoietic progenitors from peripheral blood of normal individuals or patients with polycythemia vera (PV) were cultured in methylcellulose medium containing 2.5 U/ml of erythropoietin (Ep). After 7-9 days, colonies considered to be early stage large bursts were individually removed, resuspended in a small volume of fresh methylcellulose medium, and then divided between 2 dishes. To one of ...

OBJECTIVE: Anecdotal reports have suggested mood improvement in patients with bipolar disorder immediately after they underwent an echo-planar magnetic resonance spectroscopic imaging (EP-MRSI) procedure that can be performed within clinical MR system limits. This study evaluated possible mood improvement associated with this procedure. METHOD: The mood states of subjects in an ongoing EPMRSI s...

This paper presents an incentive based smart dynamic pricing scheme for consumers facilitating a hierarchical scoring mechanism. This mechanism is applied between consumer agents (CA) to electricity provider agent (EP) and EP to Generation Company (GENCO). Based on the Continuous Ranked Probability Score (CRPS), a hierarchical scoring system is formed among these entities. As CA receives the dy...

The hydrolysis of (14)C-labeled ribulose-1,5-bisphosphate carboxylase (RuBPCase) by two partially purified endoproteinases from senescing barley (Hordeum vulgare v. Numar) leaves is described. The major thiol proteinase, EP(1), exhibits biphasic kinetics which appear to be caused by a region of the large subunit of RuBPCase that is highly sensitive to attack by EP(1). This proteinase further hy...

Erythropoietin (Ep), insulin, and prostaglandins E1 and A1 (PGE1, PGA1) enhanced heme synthesis by mitochondria isolated from embryonic and adult mouse liver cells. The combination of Ep with PGE1 had an antagonistic effect, while that of Ep with PGA1 gave an additive result. The capability of isolated human platelet mitochondria to synthesize heme was also shown. This activity was stimulated b...

Inclines are additively idempotent semi rings in which products are less than or equal to either factor.The Characterization of EP elements, Product of EP elements in an incline with involution are obtained as a generalization and development of EP elements in a *regular ring and of EP elements in a reflexive semi group. Mathematics Subject Classification: 16Y60, 15A09

the purpose of this study, was to evaluate the use of echinacea purpurea (ep) root as a feed additive in broiler chicken diets. 340 7-d-old male broilers (ross 308) were randomly allocated into 5 experimental treatments (with 4 replicates) including control diet without additive, experimental diet supplemented by flavophospholipol (fl) (650 ppm) and three experimental diets were supplemented by...

Background: Toll-like receptors (TLRs) play a crucial role in early host defense against invading pathogens. Recognition of some bacterial pathogen associated molecular patterns (PAMPs) is mediated by TLR2, 4 and 5 while TLR3 distinguishes double stranded RNA. Interactions between the immune system and female reproductive system have important consequences for fertility and reproductive health....