نتایج جستجو برای: مدل بزرگ مقیاس vic 3l

تعداد نتایج: 169625  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2016
Dong-Xiu Zhang Donald L Nuss

Transmission of mycoviruses that attenuate virulence (hypovirulence) of pathogenic fungi is restricted by allorecognition systems operating in their fungal hosts. We report the use of systematic molecular gene disruption and classical genetics for engineering fungal hosts with superior virus transmission capabilities. Four of five diallelic virus-restricting allorecognition [vegetative incompat...

Alireza Aliabadi, Amir Kiani Elham Eghbalian

  Objective(s): Nowadays, cancer is an important public health problem in all countries. Limitations of current chemotherapy for neoplastic diseases such as severe adverse reactions and tumor resistance to the chemotherapeutic drugs have been led to a temptation for focusing on the discovery and development of new compounds with potential anticancer activity.   Materials and Metho...

Journal: :Revista brasileira de psiquiatria 2017
Brisa S Fernandes Michael Berk

Staging in bipolar disorder: one step closer to precision psychiatry Brisa S. Fernandes, Michael Berk IMPACT Strategic Research Centre and Barwon Health, School of Medicine, Deakin University, Geelong, VIC, Australia. Laboratório das Proteı́nas Ligantes do Cálcio no Sistema Nervoso Central, Departamento de Bioquı́mica, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. D...

2012
Andrew Burton-Jones Roger Clarke Kate Lazarenko Ron Weber

Prior research has argued that use of optional properties in conceptual models results in loss of information about the semantics of the domains represented by the models. Empirical research undertaken to date supports this argument. Nevertheless, no systematic analysis has been done of whether use of optional properties is always problematic. Furthermore, prior empirical research might have de...

Journal: :Antimicrobial agents and chemotherapy 1976
T Yamada K Masuda Y Mizuguchi K Suga

Two alleles for viomycin-capreomycin resistance (vic) in Mycobacterium smegmatis affect ribosome structures. One (vicA) affects a component of 50S subunits and the other (vicB) affects a component of 30S subunits. The locus for neomycin-kanamycin resistance (nek), which is linked to vicA and vicB, affects a component of 30S subunits. Although the erythromycin resistance locus (ery) is linked to...

2017
Tanja Schjødt Jørgensen Carl Turesson Meliha Kapetanovic Martin Englund Aleksandra Turkiewicz Robin Christensen Henning Bliddal Pierre Geborek Lars Erik Kristensen

OBJECTIVES Biologic agents have dramatically changed treatment of rheumatoid arthritis (RA). To date only scarce head-to-head data exist especially when the biological therapies are given as monotherapy without concomitant disease modifying drugs (DMARDs). Thus the objective of the current study is to evaluate treatment response of all available biological therapies with special focus on utilit...

2017
Xin Deng Peng Dong Lingling Zhang Danping Tian Lin Zhang Wei Zhang Li Li Jing Deng Peishan Ning Guoqing Hu

OBJECTIVE Published research has not considered acute diseases and injuries in assessing the impact of varying disease counts on health-related quality of life (HRQoL). We used Chinese value sets of EQ-5D-3L to examine the relationship between the number of diseases individuals had (including chronic diseases, acute diseases and injuries) and their HRQoL. METHODS A total of 19 387 individuals...

Journal: : 2022

این پژوهش با الهام گرفتن از نتایج یک طرح مطالعاتی کاربردی، رویکرد سلسله­‌مراتبی جهت پیگیری فرایند توسعه تأمین‌کنندگان و حمایت تصمیمات موجود در هر مراحل آن ارائه‌ می‌کند. ابتدا، زمینه‌های تأمین نیازمند سپس واجد شرایط هریک زمینه‌ها به کمک تصمیم‌گیری چندشاخصه بهترین-بدترین مشخص می‌گردند. معیارهای شناسایی نیز مرور مطالعات پیشین بهره‌گیری نظرات خبرگان حوزه‌ی خرید استخراج‌شده‌اند. درنهایت، مدل ریاضی ...

2015
Yan Feng Nancy Devlin Mike Herdman

BACKGROUND The EQ-5D is a brief, generic measure of health status that can be easily incorporated into population health surveys. There are two versions of the EQ-5D for use in adult populations, one with 3 response levels in each of the instrument's 5 dimensions (EQ-5D-3L) and one with 5 levels in each dimension (EQ-5D-5L). We compared the two versions as measures of self-reported health statu...

2014
Uwe Konerding Sylvia G Elkhuizen Raquel Faubel Paul Forte Tomi Malmström Elpida Pavi MF Bas Janssen

BACKGROUND Most previous studies concerning the validity of the EQ-5D-3L items refer to applications of only a single language version of the EQ-5D-3L in only one country. Therefore, there is little information concerning the extent to which the results can be generalised across different language versions and/or different countries. Here the validity of the EQ-5D-3L items is investigated for s...

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